Welcome to the Zagorski Lab


FUNDING

Active Funding

R01 NS24469 Meredith (PI)
1/1/03-12/31/08
NIH/NIG
N-Methyl and Other Peptide Inhibitors of Fibrillogenesis
My contributions to this project includes the execution and interpretation of the NMR data of the amyloid Aβ peptide and peptide inhibitors.
Role: Co-Investigator (consortium)
R01 AG027853-01 Zagorski (PI)
8/1/06-3/31/11
NIH/NIA
Mechanism of Amyloid β-Aggregation
Biophysical studies of the amyloid Aβ peptide with major focus toward disentangling the structure of the soluble aggregates, and the effects of the Met35 side chain oxidation state on the aggregation/amyloid formation.
Role: PI

Recently Completed Funding

IIRG-02-4238 Zagorski (PI)
8/1/02-7/31/05
Alzheimer's Association
The Solution Structure of α-Synuclein
The major goals of this project is to explore the aggregation of α-synuclein in water-methanol solution.
Role: PI
CHE-0407144 Guo (PI)
4/4/04-3/31/07
NSF
Synthetic and Structural Studies on Sperm CD52
The major goals are to synthesize and characterize the solution structure of the sperm Glycopeptide CD52
Role: Co-PI (0% effort) this collaboration was discontinued since the PI has relocated to another institution
S10 RR16702 Sayre (PI)
4/1/04-3/31/05
NIH
400 MHz NMR Spectrometer
This proposal was to purchase a walk up NMR instrument for the Department of Chemistry.
Role: Co-PI (0% effort)
R01 AG14363 Zagorski (PI)
4/1/00-3/31/06
NIH/NIA
Inhibition and Mechanism of Amyloid β-Aggregation
Biophysical studies of the amyloid Aβ peptide with the major focus toward elucidation of the amino acids making contacts during the early stages of aggregation.
Role: PI