Senior Instructor 
Center for Global Health & Diseases
Ph.D. 1991
Lucknow University/Central Drug Research Institute, Lucknow, India.
Biography
Dr Mehlotra's Ph.D. thesis research work included biochemical aspects of growth, differentiation, virulence, and chemotherapy of pathogenic protozoa, such as Acanthamoeba culbertsoni, Naegleria fowleri (aerobia), Entamoeba histolytica , and Giardia lamblia . He served as a full-time Lecturer in Zoology in a local undergraduate college during 1991-1995 before coming to CWRU for his post-doctoral training. Currently, Dr. Mehlotra is working with Dr. Peter Zimmerman.
Research interests
- Molecular-based epidemiology of malaria
- Genetic basis of drug resistance in malaria parasite
- Pharmacogenetics of antimalarials
- Association between red blood cell polymorphisms and malaria infection
CONTACT INFORMATION
Phone: 216-368-6172
Fax: 216-368-4825
E-mail: rkm@case.edu
PUBLICATIONS
Search PubMed
1. R. K. Mehlotra , K. Lorry, W. Kastens, S. Miller, M. P. Alpers, M. Bockarie, J. W.Kazura and P. A. Zimmerman (2000). Random distribution of mixed species malariainfections in Papua New Guinea. American J. Tropical Medicine Hygiene, 62, 225-231.
2. A. A. R. Tobian, R. K. Mehlotra , P. Mungai, I. Malhotra, A. Wamachi, D. Koech,J. Ouma, P. Zimmerman and C. L. King (2000). Frequent cord and maternal bloodinfections with Plasmodium falciparum , P. malariae , and P. ovale in Kenya.J. Infectious Diseases, 182, 558-563.
3. S. S. Patel, R. K. Mehlotra , W. Kastens, C. S. Mgone, J. W. Kazura and P. A. Zimmerman (2001). The association of the glycophorin C exon 3 deletion with ovalocytosis and malaria susceptibility in the Wosera, Papua New Guinea. Blood, 98, 3489-3491.
4. R. K. Mehlotra , H. Fujioka, P. D. Roepe, O. Janneh, L. M. B. Ursos, V. Jacobs-Lorena, D. T. McNamara, M. J. Bockarie, J. W. Kazura, D. E. Kyle, D. Fidock and P. A. Zimmerman (2001). Evolution of a unique Plasmodium falciparum chloroquine resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America. PNAS, USA, 98, 12689-12694.
5. R. K. Mehlotra , L. J. Kasehagen, M. Baisor, K. Lorry, J. W. Kazura, M. J. Bockarie, and P. A. Zimmerman (2002). Malaria infections are randomly distributed in diverse holoendemic areas of Papua New Guinea. American J. Tropical Medicine Hygiene, 67, 555-562.
6. P. A. Zimmerman, R. K. Mehlotra , L. J. Kasehagen and J. W. Kazura (2004). Why do we need to know more about mixed Plasmodium species infections? Trends in Parasitology, 20, 440-447.
7. R. K. Mehlotra , G. Mattera, K. Bhatia, J. C. Reeder, M. Stoneking and P. A. Zimmerman (2005). Insight into the early spread of chloroquine resistant Plasmodium falciparum in Papua New Guinea (J. Infectious Diseases, In press).
8. R. K. Mehlotra , M. Ziats, M. Bockarie and P. A. Zimmerman (2005). CYP2B6 gene polymorphisms associated with reduced drug metabolism in malaria-endemic Papua New Guinean and West African populations (Manuscript submitted to European J. Clinical Pharmacology).
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