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Congressman Regula visits national center he helped create

Congressman Ralph Regula (R-16th) of Ohio visited the National Center for Regenerative Medicine in Cleveland on March 21. Regula was the driving force behind establishing the center through a $4.5 million federal appropriation to seed its development.

The center is a cooperative venture among the Case Western Reserve University, The Cleveland Clinic Foundation and University Hospitals of Cleveland. The center builds on existing excellence at the affiliated institutions in heart disease, non-embryonic stem cell transplantation, cancer, genetic disorders, and neurodegenerative diseases, such as multiple sclerosis and Alzheimer’s disease. This was Regula’s first visit to the institutions since the passing of the appropriation bill by Congress last November.

Congressman Regula's itinerary included stops at the Clinic's Lerner Research Institute and Case and University Hospital of Cleveland's Iris S. and Bert L. Wolstein Research Building. Following meetings with a patient from University Hospitals of Cleveland whose life was saved from a stem cell transplant, and doctors and scientists who specialize in stem cell research and treatment, the congressman discussed the progress at the center with Edward M. Hundert, M.D., Case president; Ralph I. Horwitz, M.D., dean of the School of Medicine; Delos M. Cosgrove, M.D., president and chief executive officer of The Cleveland Clinic; Eric J. Topol, M.D., chief academic officer and chair of the department of cardiovascular medicine at The Cleveland Clinic and a professor of medicine for the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University; Thomas F. Zenty, III, chief executive officer of University Hospitals Health System; and Fred C. Rothstein, M.D., president and chief executive officer of University Hospitals of Cleveland.

The center’s research facilities, located at Case, University Hospitals of Cleveland and the Cleveland Clinic, will enable new non-embryonic stem cell research discoveries to be translated into therapies that can be used to treat thousands of patients each year. In addition, the center’s education programs will train personnel such as nurses, students, and technicians to perform groundbreaking research and deliver the world’s foremost patient care.

Among the continuing research at the National Center for Regenerative Medicine:

  • Exploring the use of stem cells derived from the umbilical cords of newborn babies as a new, viable and effective source for cellular transplantation for thousands of leukemia patients who would have no other treatment option.
  • Investigating the regeneration of neurons and glial cells for the potential treatment of spinal cord injuries, Alzheimer’s disease and multiple sclerosis.
  • Defining treatments using non-embryonic stem cells to grow new blood vessels to replace damaged ones, and having the potential to augment conventional therapies such as artery bypass grafting and angioplasty.
  • Studying the use of non-embryonic stem cells to treat musculoskeletal disorders that are caused by degeneration or traumatic damage of bones and cartilage, including degenerative joint disease, complex bone fractures, dental disease, and severe skin disorders.

The director of the National Center for Regenerative Medicine is Stanton L. Gerson, M.D., who is the Shiverick Professor of Hematological Oncology at the Case School of Medicine and director of The Ireland Cancer Center at University Hospitals of Cleveland. The co-director is Paul DiCorleto, Ph.D., who is the chairman of the Lerner Research Institute of The Cleveland Clinic.

In addition to the federal funding, Case, the Cleveland Clinic and University Hospitals of Cleveland, along with Athersys, Inc., and other research partners, have received $19.5 million from the State of Ohio to create the Wright Center of Innovation for Stem Cell and Regenerative Medicine. The grant represents nearly $10.9 million in funding from Ohio’s Wright Capital Fund and $8.6 million from the state’s Biomedical Research and Technology Transfer Fund.

The Center for Stem Cell and Regenerative Medicine and the National Center for Regenerative Medicine are integrated and focus, respectively, on the research and practical, clinical aspects of regenerative medicine to treat human disease.

This funding represents an investment to make Cleveland a national leader in nonembryonic stem cell research and regenerative medicine, which in turn can help diversify the local and state economy which historically has been reliant on manufacturing.

 

 

About Case Western Reserve University

Case is among the nation's leading research institutions. Founded in 1826 and shaped by the unique merger of the Case Institute of Technology and Western Reserve University, Case is distinguished by its strengths in education, research, service, and experiential learning. Located in Cleveland, Case offers nationally recognized programs in the Arts and Sciences, Dental Medicine, Engineering, Law, Management, Medicine, Nursing, and Social Work. http://www.case.edu.