Mukesh K. Jain, MD, FAHA

Director, Case Cardiovascular Research Institute

Mukesh K. Jain, MD, FAHA, is the Director of the Case Cardiovascular Research Institute at Case Western Reserve University and the Ellery Sedgwick Jr. Chair & Distinguished Scientist University Hospitals Case Medical Center. He graduated summa cum laude from the University of Buffalo School of Medicine. He completed his internal medicine residency at the Beth Israel Hospital, Harvard Medical School followed by a research fellowship at Harvard. Dr. Jain completed his Cardiovascular Medicine fellowship at Brigham and Women's Hospital and then joined the faculty from 2000-2006. There he rose through the ranks and eventually became Director of the Program in Cardiovascular Transcriptional Biology at Harvard Medical School.

Dr Jain's main area of research interest is the basic mechanisms governing cellular development and function. His laboratory identified a family of factors termed Kruppel-like Factors that regulate critical aspects of heart and blood vessel biology. These research efforts have spawned novel areas of investigation with therapeutic implications for a broad spectrum of pathologic states including chronic inflammatory disorders, heart failure, metabolic dysregulation, and regenerative medicine. His research has been supported by grants from the National Institutes of Health, American Heart Association, American Diabetes Association, and the Alliance for Cancer Gene Therapy.

A recipient of numerous awards, Dr Jain was elected into the prestigious American Society for Clinical Investigation, Association of American Physicians, and is a Fellow of the American Heart Association. Dr. Jain was recipient of the Harvard Medical School's 2005 Mentorship Award and the CWRU/UHCMC Agre Award (2009) for his efforts in fostering the career of young investigators - many of whom have established research programs across the globe. Dr Jain has published extensively in peer-reviewed basic science journals and serves on the Editorial Boards of the Journal of Clinical Investigation, Circulation Research, Arteriosclerosis, Thrombosis, and Vascular Biology, and the Journal of Molecular and Cellular Cardiology.