Joseph E. Willis, M.D.Associate Professor
11100 Euclid Ave.
Cleveland, OH 44106
phone: (216) 844-8292
|1982||M.B. B.Ch. B.A.O., University College, Cork, Ireland|
|1986||F.R.C.S.I., Fellowship of the Royal College of Surgeons in Ireland|
|1987-1988||Research Fellow in the Department of Surgery, State University of New York, Buffalo, New York|
|1988-1992||Residency training in a combined AP/CP Pathology Program, University of Rochester, New York|
|1991-1992||Chief Resident, Department of Pathology, University of Rochester, New York|
|1992-1993||Fellow in Surgical Pathology, University of Michigan, Ann Arbor, Michigan|
|1993||American Board of Pathology - Combined Anatomic Pathology and Clinical Pathology|
|1993-2001||Assistant Professor, Department of Pathology, Institute of Pathology, Case Western Reserve University, Cleveland, Ohio|
|1997||American Board of Pathology - Cytopathology Subspecialty Board|
|2001-present||Associate Professor, Department of Pathology, Institute of Pathology, Case Western Reserve University, Cleveland, Ohio|
|2004-present||Director, Tissue Management, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio|
|2005-present||Vice Chair of Pathology for Clinical Affairs, UH Case Medical Center/Case Western Reserve University, Cleveland, Ohio|
Gastrointestinal Pathology - investigating basic mechanisms of development and prognostic factors relating to gastro-intestinal neoplasms.
Aberrant vimentin methylation is characteristic of upper gastrointestinal pathologies.
Moinova H, Leidner RS, Ravi L, Lutterbaugh J, Barnholtz-Sloan JS, Chen Y, Chak A, Markowitz SD, Willis JE.
Cancer Epidemiol Biomarkers Prev. 2012 Apr;21(4):594-600.
Variation in age at cancer diagnosis in familial versus nonfamilial Barrett's esophagus.
Chak A, Chen Y, Vengoechea J, Canto MI, Elston R, Falk GW, Grady WM, Guda K, Kinnard M, Markowitz S, Mittal S, Prasad G, Shaheen N, Willis JE, Barnholtz-Sloan JS.
Cancer Epidemiol Biomarkers Prev. 2012 Feb;21(2):376-83. doi: 10.1158/1055-9965.EPI-11-0927.
Aberrantly methylated PKP1 in the progression of Barrett's esophagus to esophageal adenocarcinoma.
Kaz AM, Luo Y, Dzieciatkowski S, Chak A, Willis JE, Upton MP, Leidner RS, Grady WM.
Genes Chromosomes Cancer. 2012 Apr;51(4):384-93.
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.
Zhou D, Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, Dawson D, Willis JE, Markowitz SD, Camargo FD, Avruch J.
Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1312-20. 31.
Image analysis for classification of dysplasia in Barrett's esophagus using endoscopic optical coherence tomography.
Qi X, Pan Y, Sivak MV, Willis JE, Isenberg G, Rollins AM.
Biomed Opt Express. 2010 Sep 9;1(3):825-847