Howard Meyerson, M.D.

Associate Professor

Mailing Address:
11100 Euclid Ave.
Cleveland, OH 44106

phone: (216) 844-1848
email: Howard.Meyerson@Case.edu

Biography

1983 B.A. with Distinction, Biochemistry and Molecular Biology, Northwestern University, Evanston, Illinois
1987 M.D., Case Western Reserve University, Cleveland, Ohio
1987-1990 Anatomic Pathology Resident, Department of Pathology, Case Western Reserve University and University Hospitals of Cleveland
1990-1991 Immunopathology Fellow, Department of Pathology, Case Western Reserve University and University Hospitals of Cleveland
1991-1994 NIH Postdoctoral Fellow National Research Service Award
1991-1993 Clinical Pathology Resident, Department of Pathology, Case Western Reserve University and University Hospitals of Cleveland
1994-1996 Hematopathology Fellow, Department of Pathology, Case Western Reserve University and University Hospitals of Cleveland
1996-1997 Instructor in Pathology, Department of Pathology, Case Western Reserve University
1997-present Assistant Professor, Department of Pathology, Case Western Reserve University
1998-present Director of Hematopathology, University Hospitals of Cleveland
1996-2000 Director, Clinical Pathology Resident Training, University Hospitals of Cleveland
2000-present Director of Flow Cytometry, University Hospitals of Cleveland


Research
My work has focused on the analysis and classification of hematopoietic neoplasms and the flow cytometric analysis of these disorders. I am in involved in collaborative work using high resolution phenotypic analysis- amplification staining techniques for the evaluation of these neoplasms. I also am involved in several collaborations in the analysis of immune cell subsets in a variety of disorders and therapeutic interventions.

Publications
Meyerson HJ, Huang JH, Fayen JD, Getty R, Greenspan NS, Tykocinski ML (1996) Functional dissociation of CD8alpha's immunoglobulin homologue and connecting peptide domains. J Immunol 156,574-584.

Meyerson HJ, Farhi D, Rosenthal N (1998) Transient increase in blasts mimicking AML or MDS following growth factor therapy. Am J Clin Path 109, 675-681.

Chen A, Meyerson HJ, Salvekar A, Tykocinski ML (1998) Non-glycosylated human B7-1 (CD80) retains the capacity to bind to its counter-receptors. FEBS Lett 428, 127-134.

Antall PM, Meyerson HJ, Kaplan D, Venglarcik J, Hostoffer RW (1999) Selective anti-polysaccharide antibody deficiency associated with peripheral blood CD5 positive B cell predominance. J Allergy Clin Immunol 103, 637.

Patki AH, Purvis SF, Meyerson HJ, Lederman MM (1999) Lymphocyte proliferation assays may underestimate antigen responsiveness in human immunodeficiency virus infection. Clin Immunol 93, 245-249.

Koc ON, Gerson SL, Cooper BW, Laughlin M, Meyerson H, Kutteh L, Fox RM, Szekely EM, Tainer N, Lazarus HM (2000). Randomized crossover trial of progenitor cell mobilization: high dose cyclophosphamide plus G-CSF versus GM-CSF plus G-CSF. J Clin Oncol 18, 1824-1830

Edelman J, Meyerson HJ (2000) Diminished CD3 expression is useful for detecting and enumerating Sezary cells. Am J Clin Path 114, 467-477.

Salkowitz J, Purvis S, Meyerson H, Zimmerman P, O'Brien T, Aledort L, Eyster ME, Hilgartner M, Kessler C, Konkle B, White G, Goedert J, Lederman M (2001) Characterization of high-risk HIV-1 seronegative hemophiliacs. Clin Immunol 98, 200-211.

Villella A, Picard C, Jouanguy E, Popko S, Meyerson H, Abughali N, Casanova J-L, Hostoffer RW (2001) Recurrent mycobacterial avium osteomyelitis associated with a novel dominant interferon gamma receptor mutation. Pediatrics 107, e47

Kaplan D, Meyerson HJ, Lewandowski C (2001) High resolution immunophenotypic analysis of chronic lymphocytic leukemia cells by enzymatic amplification staining (EAS). Am J Clin Path 116, 429-436.