James SWAIN, PhD, RD, LD
BACKGROUND
James received his Ph.D. in Human Nutrition from Iowa State University (2000). His thesis focused on two areas: identifying and characterizing beef proteins found to influence nonheme iron bioavailability and evaluating iron indexes and total antioxidant status in response to soy protein intake in perimenopausal women.
Dr. Swain is a registered, licensed dietitian. The clinical rotation of his dietetic internship was at Mercy Hospital, Des Moines, Iowa. Recently, he was a postdoctoral fellow studying the bioavailability of iron fortificants at a U.S. Department of Agriculture, Agricultural Research Service human nutrition research center in Grand Forks, North Dakota.
He joined the Nutrition faculty at Case Western Reserve University as Assistant Professor in August 2003. In addition to his teaching and research activities, he is director of the Nutrition Department’s nationally accredited (CADE) Didactic Program in Dietetics (DPD).
EDUCATION
1993: B.A. Major: Biological Sciences
University of California (Santa Barbara)
1996: M.S. Major: Family and Consumer Sciences
Cal. State University (Northridge)
2000: Dietetic Internship -> Clinical Rotation
Mercy Hospital, Des Moines IA
2000: Ph.D. Major: Nutrition
Iowa State University
RESEARCH INTERESTS
(i) My research expertise and focus is in the area of iron bioavailability and food fortification using different forms of iron. My research also focuses on understanding the influence of dietary iron on intestinal tumorigenesis, using immunohistochemistry, proteomics, and gene expression analysis.
RECENT PUBLICATIONS
Sean R Lynch, Thomas Bothwell, and the SUSTAIN Task Force on Iron Powders (Lou Campbell, Kristina Cowan, Ray Glahn, Leif Hallberg, Michael Hoppe, Lena Hulthen, Janet R Hunt, Richard F Hurrell, Dennis Miller, James H Swain, Liz Turner, Pattanee Winichagoon, C.K. Yeung, Christophe Zeder, and Michael B Zimmermann). "A Comparison of Physical Properties, Screening Procedures and a Human Efficacy Trial for Predicting the Bioavailability of Commercial Elemental Iron Powders Used for Food Fortification." Int. J. Vitam. Nutr. Res.; 77(2): 107-124, 2007.
James H Swain, Johnson LK, Penland JG and Hunt JR. "Combating iron deficiency: Electrolytic iron or ferrous sulfate increased body iron in women with moderate to low iron stores." J. Nutr.; 137: 620-627, 2007.
James H Swain, Johnson, LK and Hunt, JR. "An irradiated electrolytic iron fortificant, poorly absorbed by human subjects, is also less responsive to the enhancing effect of ascorbic acid." J. Nutr.; 136: 2167-2174, 2006.
Petersen, HL, Peterson, CT, Reddy, MB, Hanson, KB, Swain JH, Sharp, RL and Alekel, DL. "Body composition, dietary intake and iron status of female collegiate swimmers." Intl. J. Sport Nutr. And Exercise Metab.; 16: 281-295, 2006.
Swain JH, Newman SM, and Hunt JR. "Bioavailability of elemental iron powders to rats is less than bakery-grade ferrous sulfate and predicted by iron solubility and particle surface area." J Nutr.; 133(11): 3546-52, 2003.
James H. Swain, D. Lee Alekel, Sarah B. Dent, Charles T. Peterson, and Manju B. Reddy. "Iron indexes and total antioxidant status in response to soy protein intake in perimenopausal women." Am. J. Clin. Nutr.; 76: 165-171, 2002.
James H. Swain, Louisa B. Tabatabai, and Manju B. Reddy. "Histidine content of low molecular weight beef proteins influences nonheme iron absorption in Caco-2 cells." J. Nutr.; 132: 245-251, 2002.
Sarah B. Dent, Charles T. Peterson, Larry D. Brace, Kathy B. Hanson, James H. Swain, Manju B. Reddy, Jennifer G. Robinson, and D. Lee Alekel. "Soy protein intake by perimenopausal women does not affect circulating lipids and lipoproteins or coagulation and fibrinolytic factors." J. Nutr.; 131: 2280-2287, 2001.
PubMed
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