Multi-disciplinary research combining epidemiologic studies and clinical trials in TB endemic countries with modern microbiology, immunology, and genetics is essential to make progress in the fight against TB. The NIH-funded Tuberculosis Research Unit (TBRU) is a leader in interdisciplinary TB research. The TBRU aims not only to understand how M. tuberculosis infects, persists, and causes disease in humans, but also to translate that understanding into improving prevention, vaccines, diagnostics, and drug treatment for TB.
Since its foundation in 1994, the Case Western Reserve University Center for Aids Research (Case CFAR) has been a center of excellence for both clinical and basic AIDS research. As the only NIH-funded CFAR in the Midwestern United States, we have provided our 174 members with national and international research, especially with respect to research in tuberculosis and HIV malignancy, microbicides, pathogenesis, virology, clinical trials, and training. As the first CFAR to make a major investment in international research, we have been able to expand a highly productive and long-standing (21 year) scientific relationship with Makerere University, Kampala, Uganda.
CDC’s Office of Safety, Health, and Environment serves as a leader in the field of biosafety. CDC partners with the U.S. National Institutes of Health to publish biosafety guidelines for protecting workers and preventing exposures in biological laboratories. CDC’s Office of Safety, Health, and Environment serves as the World Health Organization’s Centre for Applied Biosafety Programmes and Training. CDC partners with renowned organizations to sponsor a biennial International Symposium on Biosafety and other occupational health and safety conferences. In addition, CDC’s Office of Safety, Health, and Environment has produced online training on laboratory biosecurity and offers other downloadable materials that may be useful to laboratorians nationally, or around the world.