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Case Western Reserve University

MOLECULAR BIOLOGY
and MICROBIOLOGY

 
 
       
 

 

Kenneth Yan


Cell Biology Student

Works in: Rich Lab

email: kxy63@case.edu

Education:
Chemical Engineering and Biology, Massachusetts Institute of Technology, 2008


   
 

Research:
Gliomas stem cells (GSCs) are a neoplastic subpopulation within glioblastoma multiforme (GBM) that are capable of self-renewal and driving tumor propagation. GSCs have been demonstrated to play critical roles in therapeutic resistance, tumor angiogenesis, invasion, and metastasis. Bone morphogenetic proteins (BMPs) have been shown to induce differentiation in GSCs, reducing their tumorigenic potential.  My research is investigating the potential protective role of BMP antagonists within the GSC niche.