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Research:
I am working on HDAC complexes, focusing my research on one of the
components of the HDAC complexes and I am trying to dissect its
specific role as a transcriptional repressor of HIV-1 LTR promoter.
Select Publications:
Kim YK, Cyril F. Bourgeois, Richard Pearson, Mudit Tyagi, Michelle J. West, Julian Wong, Shwu-Yuan Wu, Cheng-Ming Chiang, and Jonathan Karn: Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency. EMBO J. 2006 Aug 9;25(15):3596-604. Epub 2006 Jul 27.
Pantano S, Tyagi M, Giacca M, Carloni P. Molecular dynamics simulations on HIV-1 Tat. Eur Biophys J. 2003 Nov 8 [Epub ahead of print]. [PubMed]
Pantano S, Tyagi M, Giacca M, Carloni P. Amino acid modification in the HIV-1 Tat basic domain: insights from molecular dynamics and in vivo functional studies. J Mol Biol. 2002 May 17;318(5):1331-9. [PubMed]
Silhol M, Tyagi M, Giacca M, Lebleu B, Vives Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat. Eur J Biochem. 2002 Jan;269(2):494-501. [PubMed]
Riccardo A. G. Cinelli, Vittorio Pellegrini, Aldo Ferrari, Paolo Faraci, Riccardo Nifosi, Mudit Tyagi, Mauro Giacca and Fabio Beltram. Green Fluorescent protein as optically-controllable elements in bioelectronics. Appl.Phys.Lett. 2001 Nov 12; 79: 3353-3355.
Alessandro Marcello, Riccardo A. G. Cinelli, Aldo Ferrari, Anna Signorelli, Mudit Tyagi, Vittorio Pellegrini, Fabio Beltram and Mauro Giacca Visualization of direct interaction between HIV-1 Tat and human cyclin T1 and its sub-cellular localization. J Biol Chem. 2001 Oct 19;276(42):39220-5. [PubMed]
Cinelli RA, Tozzini V, Pellegrini V, Beltram F, Cerullo G, Zavelani-Rossi M, De Silvestri S, Tyagi M, Giacca M. Coherent dynamics of photoexcited green fluorescent proteins. Phys Rev Lett. 2001 Apr 9;86(15):3439-42. [PubMed]
Tyagi M, Rusnati M, Presta M, Giacca M.Internalization of HIV-1 Tat Requires Cell Surface Heparan Sulfate Proteoglycans. J Biol Chem. 2001 Feb 2;276(5):3254-3261. [PubMed]
Riccardo A. G. Cinelli, Aldo Ferrari, Vittorio Pellegrini, Anna Signorelli, Mudit Tyagi, Mauro Giacca, and Fabio Beltram. Engineering Single-Molecule Fluorescence Dynamics for Advanced Biomolecular Applications. Aust. J. Chem. 2001. 54, 107-111.
Rusnati M, Taraboletti G, Urbinati C, Tulipano G, Giuliani R, Molinari-Tosatti MP, Sennino B, Giacca M, Tyagi M, Albini A, Noonan D, Giavazzi R, Presta M. Thrombospondin-1/HIV-1 tat protein interaction: modulation of the biological activity of extracellular Tat. FASEB J. 2000 Oct;14(13):1917-30. [PubMed]
Cinelli RA, Ferrari A, Pellegrini V, Tyagi M, Giacca M, Beltram F. The enhanced green fluorescent protein as a tool for the analysis of protein dynamics and localization: local fluorescence study at the single-molecule level. Photochem Photobiol. 2000 Jun;71(6):771-6. [PubMed]
Marzio G*, Tyagi M*, Gutierrez MI, Giacca M. HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter. Proc Natl Acad Sci U S A 1998 Nov 10;95 (23):13519-24. [PubMed] *Authors contributed equally
Tulasiram P, Tyagi M, Srinivas K, Prabhudas K, Natarajan C, Suryanarayana VVS. Antigenic variation in Foot and Mouth Disease Virus type Asia1 isolates circulated during 1993-95 in India. Virus Genes 1997,15 (3): 247-53. [PubMed]
Additional Publications
Book:
Marzio, G., Tyagi, M., Gutierrez, M.I., and Giacci, M. (2000). Chromatin structure and transcriptional activation of the integrated human iimmunodeficiency virus type-1 promoter. In Advances in Animal Virology, S. Jameel, and L. Villarreal, eds. (New Delhi, India, Oxford & IBH Publishing Co. Pvt. Ltd.), pp. 143-160.
Patent:
Tyagi, M., Giacca, M. Beltram, F. Cinelli, R.A.G., Ferrari, A. Pellegrini, V. Novel mutant of the green fluorescent protein (GFP) with an optically controllable configuration. 2000. Italian Patent Application No. To / 2000 A000772.
Accession Numbers of Sequences Submitted to the Gene Bank:
1) X88858, 2) X88857, 3) X88856, 4) X88855, 5) X88859, 6) X88860
This web page is updated regularly, for the most recent complete list of publications, please contact this researcher. |
