Research
Currently I am investigating mechanisms of HIV-1 latency. Specific work focuses on the contribution of post-transcriptional mechanisms to HIV latency and ways to reverse latency in vivo.
Selected Publications:
Lassen KG, Ramyar KX, Bailey JR, Zhou Y, Siliciano RF: A critical post-transcriptional block in HIV gene expression contributes to latency in vivo. (out for review)
Lassen KG, Han Y, Zhou Y, Siliciano J, Siliciano RF: The Multifactorial Nature of HIV-1 Latency. Trends in Molecular Medicine. 2004, 10:525-31 [PubMed]
Lassen KG, Bailey JR, Siliciano RF: Analysis of human immunodeficiency virus type 1 transcriptional elongation in resting CD4+ T cells in vivo. J Virol. 2004, 78:9105-9114. [PubMed]
Han Y., Lassen K., et al. (2004) Resting CD4+ T cells from HIV-1 -infected individuals carry integrated HIV-1 genomes within actively transcribed host genes. J. Virol. 2004, 78, 6122-6133 (joint first author) [PubMed]
Complete list of Publications |
