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case western reserve university

MOLECULAR BIOLOGY
and MICROBIOLOGY

 
 
       
 

 

Adam Burgoyne


MBIO Student

Works in: Brady-Kalnay Lab

email: adam.burgoyne@case.edu

Education:
B.S. in Molecular and Cellular Biology, Biochemistry, and French; University of Maine; 2004.


   
 

Research:
Our laboratory is interested in the role the receptor protein tyrosine phosphatase mu (PTPµ), plays in adhesion and migration of glioblastoma cells.  I am currently studying changes in migration in response to gain or loss of PTPµ and the downstream signaling pathways responsible for these changes in phenotype.

Publications:

Burgoyne, A.M., Palomo, J.M., Phillips-Mason, P.J., Burden-Gulley, S.M., Major, D.L., Zaremba, A., Robinson, S., Sloan, A.E., Vogelbaum, M.A., Miller, R.H., Brady-Kalnay, S.M. PTPµ suppresses glioma cell migration and dispersal. Neuro-Oncology, March 20, 2009. Epub ahead of print. [PubMed]

Burgoyne, A.M., Phillips-Mason, P.J., Burden-Gulley, S.M., Robinson, S., Sloan A.E., Miller, R.H., Brady-Kalnay, S.M. A proteolytically cleaved intracellular fragment of PTPµ promotes glioma cell migration and survival. Cancer Research, August 18, 2009. Epub ahead of print. [PubMed]

Ekborg NA, Morrill W, Burgoyne AM, Li L, Distel DL. CelAB, a multifunctional cellulase encoded by Teredinibacter turnerae T7902T, a culturable symbiont isolated from the wood-boring marine bivalve, Lyrodus pedicellatus.  Appl Environ Microbiol. 2007 Dec;73(23):7785-8. Epub 2007 Oct 12. [PubMed]