'Research interests includes HIV/AIDS, hemorrhagic viral fevers (Marburg and Ebola). Since 2003 until joining Graduate School at Case Western Reserve University in middle of 2009, I was involved in HIV-1 Vaccine clinical trials and Research; in Uganda with the Makerere University Walter Reed Project (MUWRP) first as a Research Assistant and later as a Laboratory Scientific Officer. MUWRP is research collaboration between the Makerere University College of Health Sciences and the U.S Military HIV Research Program. While working at MUWRP, I was involved in routine follow up of vaccinated participants through immunephenotyping, intracellular cytokine staining, viral load testing Antibody titer measurements and screening for HIV infection. I later received promotion to head the Molecular Pathology and Diagnostics section of the MWRP Laboratory. Activities in this section included routine HIV-1 subtype analysis using the Multiregion Hybridization Assay (MHAacd), Viral load testing, serology and Quantitative Real-Time PCR.
My PhD dissertation research involves the “Development and Characterization of a Multivalent, Multiclade HIV-1 vaccine encoding up to 500 HIV-1 Subtypes A and D Recombinant Envelopes”. Our hypothesis is that the immune system can recognize an infinite number of antigens simultaneous or in phases. We are therefore developing a vaccine and immunize macaques with a cocktail of tens or hundreds of pseudotyped viruses encoding different Envelope recombinants.
Eller LA, Eller MA, Ouma BJ, Kataaha P, Bagaya BS, Olemukan RL, Erima S, Kawala L, de Souza MS, Kibuuka H, Wabwire-Mangen F, Peel SA, O'Connell RJ, Robb ML, Michael NL. 2007. Large-Scale Human Immunodeficiency Virus Rapid Test Evaluation in a Low-Prevalence Ugandan Blood Bank Population. JOURNAL OF CLINICAL MICROBIOLOGY, Oct. 2007, Vol. 45, No. 10 p. 3281–3285 [PubMed]