CD40 is a member of the TNF receptor superfamily that is expressed on a variety of hematopoietic and non-hematopoietic cells. CD40 is relevant to a broad array of diseases since CD40 is crucial for protection against many pathogens (Toxoplasma, Cryptosporydium, Mycobacteria, Salmonella, Cryptococcus, etc), and CD40 drives various diseases that have an inflammatory component (atherosclerosis, inflammatory bowel disease, systemic lupus erythematosus, ischemia, graft rejection, etc). Dr. Subauste’s laboratory studies both aspects of CD40 biology with the hope of identifying new approaches for treatment of inflammatory disorders and infections controlled by CD40. The laboratory is located on the 4th floor of the BRB (448A).
Inquiries regarding positions in the laboratory should be sent to email@example.com.