The Case ACTU has been in operation since 1987 and is a leader in clinical treatment trials research for the management of HIV infection. The ACTU is one of 33 units that comprise the national Adult AIDS Clinical Trials Group (AACTG). More than 40 faculty and staff maintain the ACTU and participate in the design and implementation of new treatment trials for HIV infections and its complications, with an emphasis on trials designed to explore key questions in HIV pathogenesis. Through linkage to the Case Center for AIDS Research and its research cores, the Case ACTU has achieved top ranked status within the AACTG.
Since its foundation in 1994, the Case Western Reserve University Center for AIDS Research (Case CFAR) has been a center of excellence for both clinical and basic AIDS research. As the only NIH-funded CFAR in the Midwestern United States, we have provided our 174 members with national and international research, especially with respect to research in tuberculosis and HIV malignancy, microbicides, pathogenesis, virology, clinical trials, and training. As the first CFAR to make a major investment in international research, we have been able to expand a highly productive and long-standing (21 year) scientific relationship with Makerere University, Kampala, Uganda.