In chronological order
Yan T, Seo Y, Schupp JE, Zeng X, Desai AB, Kinsella TJ
Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence Mol Cancer Ther. 2006 Apr;5(4):893-902 Abstract
Seo Y, Yan T, Schupp JE, Yamane K, Radivoyevitch T, Kinsella TJ
The interaction between two radiosensitizers: 5-iododeoxyuridine and caffeine Cancer Res. 2006 Jan 1;66(1):490-8
Abstract
Seo Y, Yan T, Schupp JE, Radivoyevitch T, Kinsella TJ Schedule-dependent drug effects of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as an in vivo radiosensitizer in U251 human glioblastoma xenografts Clin Cancer Res. 2005 Oct 15;11(20):7499-507
Abstract
Yamane K, Kinsella TJ CK2 inhibits apoptosis and changes its cellular localization following ionizing radiation Cancer Res. 2005 May 15;65(10):4362-7
Abstract
Yamane K, Kinsella TJ Casein kinase 2 regulates both apoptosis and the cell cycle following DNA damage induced by 6-thioguanine Clin Cancer Res. 2005 Mar 15;11(6):2355-63
Abstract
Seo Y, Yan T, Schupp JE, Colussi V, Taylor KL, Kinsella TJ Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2'-deoxyribose Clin Cancer Res. 2004 Nov 15;10(22):7520-8
Abstract
Yan T, Desai AB, Jacobberger JW, Sramkoski RM, Loh T, Kinsella TJ CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses Mol Cancer Ther. 2004 Sep;3(9):1147-57
Abstract
Yamane K, Taylor K, Kinsella TJ Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chk1 pathway Biochem Biophys Res Commun. 2004 May 21;318(1):297-302
Abstract
Berry SE, Loh T, Yan T, Kinsella TJ Role of MutSalpha in the recognition of iododeoxyuridine in DNA Cancer Res. 2003 Sep 1;63(17):5490-5
Abstract
Yamane K, Chen J, Kinsella TJ Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint Cancer Res. 2003 Jun 15;63(12):3049-53
Abstract
Yan T, Berry SE, Desai AB, Kinsella TJ DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G2-M arrest in MMR-proficient RKO cells Clin. Cancer Res. 2003 Jun;9(6):2327-34
Abstract
Taverna P, Hwang HS, Schupp JE, Radivoyevitch T, Session NN, Reddy G, Zarling DA, Kinsella TJ Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization Cancer Res. 2003 Feb 15;63(4):838-46
Abstract
Yan T, Schupp JE, Hwang HS, Wagner MW, Berry SE, Strickfaden S, Veigl ML, Sedwick WD, Boothman DA, Kinsella TJ
Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation Cancer Res. 2001 Nov 15;61(22):8290-7
Abstract
Berry SE, Kinsella TJTargeting DNA mismatch repair for radiosensitization Semin Radiat Oncol. 2001 Oct;11(4):300-15
Abstract
Taverna P, Liu L, Hwang HS, Hanson AJ, Kinsella TJ, Gerson SLMethoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells Mutat Res. 2001 May 10;485(4):269-81
Abstract
Meyers M, Wagner MW, Hwang HS, Kinsella TJ, Boothman DARole of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses Cancer Res. 2001 Jul 1;61(13):5193-201
Abstract
Miyamoto S, Huang TT, Wuerzberger-Davis S, Bornmann WG, Pink JJ, Tagliarino C, Kinsella TJ, Boothman DACellular and molecular responses to topoisomerase I poisons. Exploiting synergy for improved radiotherapy Ann N Y Acad Sci. 2000;922:274-92
Abstract
Berry SE, Davis TW, Schupp JE, Hwang HS, de Wind N, Kinsella TJSelective radiosensitization of drug-resistant MutS homologue-2 (MSH2) mismatch repair-deficient cells by halogenated thymidine (dThd) analogues: Msh2 mediates dThd analogue DNA levels and the differential cytotoxicity and cell cycle effects of the dThd analogues and 6-thioguanine Cancer Res. 2000 Oct 15;60(20):5773-80
Abstract
Kinsella TJ, Schupp JE, Davis TW, Berry SE, Hwang HS, Warren K, Balis F, Barnett J, Sands HSPreclinical study of the systemic toxicity and pharmacokinetics of 5-iodo-2-deoxypyrimidinone-2'-deoxyribose as a radiosensitizing prodrug in two, non-rodent animal species: implications for phase I study design Clin.Cancer Res. 2000 Sep;6(9):3670-9
Abstract
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