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Dennis Orthopaedics Tissue Engineering Laboratory

 
 
Principal Investigator

James (Jay) Henderson


Former Postdoctoral Fellow

Now at Syracuse

 


Areas of Research:


Tissue-engineering cartilage for articular- and non-articular-cartilage applications.


Elucidating and modulating biomechanical signaling pathways to develop cell-based therapies for musculoskeletal repair and regeneration.

 

Quantitating the mechanical environment present in musculoskeletal systems during development and healing.

 

Educational Background:
 

Postdoctoral Fellow, Skeletal Research Center, Case Western Reserve University, 2004–present
Ph.D., Mechanical Engineering, Stanford University, 2004
M.S., Mechanical Engineering, Stanford University, 2001
B.S., Mechanical Engineering, Rice University, 1999

 

Selected Awards:


Arthritis Foundation Postdoctoral Fellow, 2006–present
Aspiring Investigator Award, 5th Annual Meeting of the Midwestern Tissue
Engineering Consortium, 2005
Hertz Foundation Fellow, 1999–2004
Stanford Graduate Fellow (Burt and Deedee McMurtry Fellow), 1999–2002

 

Selected Refereed Archival Journal Publications:
1) Henderson, J. H., Welter, J. F., Mansour, J. M., Niyibizi, C., Caplan, A. I., and Dennis, J. E. (2007) Cartilage tissue engineering for laryngotracheal reconstruction: comparison of chondrocytes from three anatomic locations in the rabbit. Tissue Eng, 13(4):843-53. Abstract
2) Henderson, J. H., de la Fuente, L., Romero, D., Colnot, C. I., Huang, S., Carter, D. R., and Helms, J. A. Rapid growth of cartilage rudiments may generate perichondrial structures by mechanical induction. Biomech Model Mechanobiol, in press. DOI: 10.1007/s10237-006-0038-x. Abstract
3) Henderson, J. H., Chang, L. Y., Song, H. M., Longaker, M. T., and Carter, D. R. Age-dependent properties and quasi-static strains in the rat sagittal suture. J Biomechanics, 38:2294–2301, 2005. Abstract
4) Henderson, J. H., Nacamuli, R. P., Zhao, B., Longaker, M. T., and Carter, D. R. Age-dependent residual tensile strains are present in the dura mater of rats. J R Soc Interface, 2:159–167, 2005. Abstract
5) Henderson, J. H., Longaker, M. T., and Carter, D. R. Sutural bone deposition rate and strain magnitude during cranial development. Bone 34:271–280; 2004. Abstract
6) Henderson, J. H., and Carter, D. R. Mechanical induction in limb morphogenesis: the role of growth-generated strains and pressures. Bone 31:645–653; 2002. Abstract