Dennis Orthopaedics Tissue Engineering Laboratory

In Kap Ko

Postdoctoral Research Associate Department of Orthopaedics Case Western Reserve University

Research interests:

1. Stem cell targeting by cell surface modification using tissue specific molecules.
2. Bone and cartilage tissue engineering.

EUDCATION BACKGROUND:

Ph.D (2000.4- 2003.10)
Department of regenerative materials, Institute of Frontier Medical Sciences, Kyoto University, Kyoto, Japan.

MS (1998- 2000.3)
Department of regenerative materials, Institute of Frontier Medical Sciences,
Kyoto University, Kyoto, Japan.

BE (1990-1997)
Division of Materials Sciences and engineering, College of Engineering, Hanyang University, Seoul, Korea.

PUBLICATIONS:

I. K. Ko, M. Murakami, Karen Moodie, M. Simons, J.D. Pearlman. Visible Genetics (VisGen): A New Dual Modality Contrast Agent for Quantitative Assessment of Up-regulated Gene Product Distribution. Accepted in Magnetic Resonance in Medicine.

I.K. Ko, H.T. Song, E.J. Cho, Y.M. Huh, J.S. Suh. In vivo MR imaging of tissue-engineered Human Mesenchymal Stem Cells Transplanted to the Mouse-Preliminary study. Annals of Biomedical Engineering, 35(1):101-108 (2007). Abstract

M. Nakajima, T. Ishimuro, K. Kato, I.K.Ko, I. Hirata, Y. Arima, H. Iwata. Combinatorial protein display for the cell-based screening of biomaterials that direct neural stem cell differentiation. Biomaterials, 28(6), 1048-1060 (2007). Abstract

I.K. Ko, K. Kato, and H. Iwata. A Thin Carboxymethyl Cellulose Culture Substrate for the Cellulase-Induced Harvesting of an Endothelial Cell Sheet. Journal of Biomaterials Science, Polymer Edition. 16(10), 1277-1291 (2005). Abstract

I.K. Ko, K Kato, and H. Iwata. Parallel analysis of multiple surface markers expressed on rat neural stem cells using antibody microarrays, Biomaterials, 26, 4882-4891 (2005). Abstract

I.K. Ko, K Kato, and H. Iwata. Antibody microarray for correlation of cell phenotype with surface marker, Biomaterials, 26, 687-96 (2005). Abstract

A. El-salmawy, T Kitagawa, I.K. Ko, A. Murakami, Y. Kimura, T. Yamaoka, and H. Iwata. Preparation and properties of ProNectin F-coated biodegradable hollow fibers. J Artif Organs. 8 (4), 245-251 (2005). Abstract

S. Fujita, Y. Ueda, I.K. Ko, H. J. Paek, T. Sajiki, I. Ikai, Y. Yamaoka, Y.Ikada, and H. Iwata. Functional evaluation of bioartificial liver using RT-PCR. Bio-Medical Materials and Engineering, 15 (3), 211-218 (2005). Abstract

T. Ohyama, I.K. Ko, A. Miura, H. Iwata, and W. Taki. ProNectin F-grafted-ethylene vinyl alcohol copolymer (EVAL) as a liquid type material for treating cerebral aneurysm. Biomaterials. 25(17), 3845-52 (2004). Abstract

Y. Ueda, H. Iwata, H. J. Paek, I.K. Ko, Y. Shimooka, N. Katsura, I. Ikai, Y. Yamaoka, and Y. Ikada. Bioartificial liver with whole blood perfusion. ASAIO J, 49(4), 401-406 (2003). Abstract

I.K. Ko and H. Iwata. Simple methods to give cell attachment ability to biodegradable polyester. Annals of the New York Academy of Sciences. 961,288-291 (2002). Abstract

I.K. Ko and H Iwata. An approach to constructing three-dimensional tissue. Annals of the New York Academy of Sciences. 944, 443-455 (2001). Abstract

PRESENTATIONS:

1. M. Murakami, Z.W. Zhuang, A. Helisch, I.K. Ko, N. Kahn. J. Singh, U. Deutsch, M. Simons, Fibroblast Growth Factor Receptor is Essential for Recovery from Ischemic Injury. American Heart Association 2005 (13-15 Nov, 2005, Dallas, TX).

2. H. Song, I.K. Ko, Y. Huh, S. Kim, H.Y. Kang, J. Suh. In vivo MR imaging of Tissue Engineered Human Mesenchymal Stem Cells Transplanted to the Mouse- Preliminary study. The Third Annual Meeting of The Society for Molecular Imaging (9-12 Sep, 2004, St. Louis, MO, USA)

3. I.K. Ko, K. Kato, H. Iwata. Neural stem cell surface markers analyzed by parallel cell binding assasys on antibody microarrays. 7th world biomaterials (17-21 May, 2004, Sydney, Australia)

4. I.K. Ko, K. Kato, H. Iwata. Antibody microarray for parallel analysis of neural stem cell surface markers expressed during differentiation. 2003 Japan-Taiwan Symposium on Stem cell and Tissue engineering (8 Mar, 2003, Kyoto, Japan).

5. K. Kato, I.K. Ko, I. Hirata, and H. Iwata. Global analysis of membrane proteins through direct cell binding assay on antibody microarrays. Engineering Tissue Growth International Conference and Exposition 2003 (17-20 Mar, 2003, Pittsburgh, USA).

6. S. Fujita, H.J. Paek, Y. Ueda, T. Sajiki, I.K. Ko, H. Iwata, I. Ikai, Y. Yamaoka, and Y. Ikada. Functional Evaluation of bioartificial liver using RT-PCR. ASAIO-ISAO Joint conferences (19-21 Jun, 2003, Hilton Washington, USA).

7. I.K. Ko, K. Kato, and H. Iwata. Analysis of neural cell surface antigens with an antibody microarray spotted on cellulose membrane. 5th Annual Meeting of the Tissue Engineering Society International (12-18 Dec, 2002, Kobe, Japan).

8. I.K. Ko, K. Kato, and H. Iwata. An approach to prepare an antibody microarray using a cellulose membrane and its application to the analysis of neural cell surface antigens. Tissue engineering (21-24 Nov, 2002, Cold spring harbor, New York, USA).

9. I.K. Ko and H. Iwata. Harvest of cell sheet from carboxymethyl cellulose coated surface and transferring it onto other surface. FALL MEETING OF THE KOREAN SOCIETY FOR BIOMATERIALS (4th Korean-Japan Joint Symposium on Biomaterials), (21-23 Sep, 2001, Pusan, Korea).

10. I.K. Ko and H. Iwata. An approach to constructing three-dimensional tissue. Bioartificial Organs, Tissue sourcing, Immunoisolation and Clinical Trials
(7-12 Oct, 2000, Davos, Switzerland).