Publications Escobar, P.F., Patrick, R., Rybicki, L., Al-Husaini, N., Michener, C.M., Crowe J.P. (2006) Primary gynecological neoplasms and clinical outcomes in patients diagnosed with breast carcinoma. Int J Gynecol Cancer, 1:118-22. |
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Bio Prior to joining Jeff's lab, the extent of my experience with RNA involved performing in vitro transcription experiments to study the effect of manipulating the distance between the A block and the B block promoter elements in the tRNALeu-3 gene. This gene was used as a model for studying the Saccharomyces cerevisiae SNR6 gene, which is an essential gene that is interesting in that it has an unusually long A-to-B block distance of 202 base pairs. In addition to this work, which was performed under the direction of Dr. Mike Martin at John Carroll University, another part of my Master’s project involved studying whether the architectural protein Nhp6p, which stimulates SNR6 transcription, preferentially binds certain SNR6 sequences. The amazing time that I had performing research during graduate school solidified my desire to continue working in a research laboratory, and this led me to seek my current position in the Coller lab. Here, I am thrilled to have the opportunity to take part in exploring the extraordinary world of mRNA decay. Currently, my work focuses on studying the role of decapping activators during mRNA turnover. |
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