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P10101371

Najwa Al-Husaini (Research Associate II)

Center for RNA Molecular Biology, Case Western Reserve University, School of Medicine, Wood Bldg.  W113, 10900 Euclid Ave., Cleveland OH 44106-4960, USA

E nsa29@case.edu

P 216.368.0276

F 216.368.2010

Education

John Carroll University, University Heights, OH 2006 (B.S. in Biology)

John Carroll University, University Heights, OH 2009 (M.S. in Biology)

Professional Experience

Graduate Assistant, John Carroll University Biology Department, University Heights,OH 2006-2008

Research Intern, Cleveland Clinic Breast Center, Cleveland, Ohio 2004

Honors and Awards

Recipient of the Outstanding Biology Graduate Student Award, John Carroll University, 2008

Publications

Escobar, P.F., Patrick, R., Rybicki, L., Al-Husaini, N., Michener, C.M., Crowe J.P. (2006) Primary gynecological neoplasms and clinical outcomes in patients diagnosed with breast carcinoma. Int J Gynecol Cancer, 1:118-22.

Bio

Prior to joining Jeff's lab, the extent of my experience with RNA involved performing in vitro transcription experiments to study the effect of manipulating the distance between the A block and the B block promoter elements in the tRNALeu-3 gene. This gene was used as a model for studying the Saccharomyces cerevisiae SNR6 gene, which is an essential gene that is interesting in that it has an unusually long A-to-B block distance of 202 base pairs. In addition to this work, which was performed under the direction of Dr. Mike Martin at John Carroll University, another part of my Master’s project involved studying whether the architectural protein Nhp6p, which stimulates SNR6 transcription, preferentially binds certain SNR6 sequences. The amazing time that I had performing research during graduate school solidified my desire to continue working in a research laboratory, and this led me to seek my current position in the Coller lab. Here, I am thrilled to have the opportunity to take part in exploring the extraordinary world of mRNA decay. Currently, my work focuses on studying the role of decapping activators during mRNA turnover.