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Jeff Coller, Ph.D. (Principal Investigator) |
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P 216.367.2363 F 216.368.2010 AIM jmcoller@mac.com |
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Center for RNA Molecular Biology, Case Western Reserve University, School of Medicine, Wood Bldg. W113, 10900 Euclid Ave., Cleveland OH 44106-4960, USA |
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Primary Appointment: Assistant Professor in The Center for RNA Molecular Biology |
Secondary Appointments: Biomedical Sciences Training Program Cellular and Molecular Biology Trainer |
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Education University of Michigan 1990-1994 (BS in Biology/Chemistry) Stockholm University 1993 (Visiting Scientist) University of Wisconsin-Madison 1994-2000 (Ph.D. in Cell and Molecular Biology) Howard Hughes Medical Institute / University of Arizona 2000-2005 (Post-doctoral Fellow) |
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Bio I have a long standing fascination with the study of RNA that dates back more than 15 years. My interest stems from undergraduate work I conducted on group I introns in Dr. Britt-Marie Sjöberg’s lab at Stockholm University in Sweden. Following that experience, I was drawn to the University of Wisconsin-Madison for graduate school where I immersed myself in the rich culture of RNA research that occurs at that institution. My Ph.D. work was performed in the lab of Dr. Marv Wickens; I was attracted to Marv’s lab because I was fascinated by the observation that most early developmental decisions in the embryo do not occur as a consequence of gene transcription, rather, most are made by regulating the translational status of maternal mRNAs. Following completion of my graduate work, I continued to study the process of mRNA translation as a Post-doc in Dr. Roy Parker’s lab (University of Arizona, HHMI). During the course of our work, Roy and I realized that the active regulation of mRNA translation is not an event reserved solely for the embryo, rather, it most likely occurs in all cells and is ancient in origin. I recently left Roy’s lab as I was most fortunate to have the opportunity to start my own lab in an environment renowned for its RNA community, Case Western Reserve University (CWRU). Now, as a primary investigator in the Center for RNA Molecular Biology at CWRU, I continue to explore an intriguing aspect of gene expression that involves the active movement of mRNA in and out of translation. |
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