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CWRU School of Medicine:

Cell and Molecular Biology Training Program



CMB Trainers


Name/Degree(s)

Primary Appointment

Research Interest

Derek Abbott, MD PhD

Pathology

Control of innate immune response signaling by NOD2 dependent ubiquitinylation

Erik Andrulis, PhD

Molecular Biology and Microbiology

Structure and function of ribonucleases involved in mRNA turnover

Eric Arts, PhD

Medicine (Molecular Biology and Microbiology)

Mechanisms and emergence of HIV-1 drug resistance

Kristian Baker, PhD

RNA Center (Biochemistry)

Nonsense mediated mRNA decay; mRNA quality control

Susann Brady-Kalnay, PhD

Molecular Biology and Microbiology

Role of receptor tyrosine phosphatases in axon guidance in the visual system

Heather Broihier, PhD

Neurosciences

Molecular and cellular mechanisms of Drosophila motor neuron development and migration

Paul Carey, PhD

Biochemistry

Raman spectroscopy to probe the structure and dynamics of enzyme-substrate intermediates

Cathleen Carlin, PhD

Molecular Biology and Microbiology

Receptor tyrosine kinase signaling, adenovirus control of endocytosis and protein sorting

Mark Chance, PhD

Proteomics Center (Genetics)

Proteomics; macromolecular structure; biomarkers

Jeffrey Coller, PhD

RNA Center (Biochemistry)

Molecular mechanisms of regulation of mRNA turnover in yeast

Piet de Boer, PhD

Molecular Biology and Microbiology

Dynamics and regulation of E. coli cell division

Evan Deneris, PhD

Neurosciences

Development of seratonergic neurons, developmental control of gene expression

George Dubyak, PhD

Physiology and Biophysics

Extracellular nucleotide receptors in inflammatory and cardiovascular signal transduction

Robert Ewing, PhD

Proteomics Center (Genetics)

Proteomics methods development and application

Paul Fox, PhD

CCF (Molecular Biology and Microbiology)

Molecular mechanisms of post-transcriptional control of gene expression in inflammation responses

Stanton Gerson, MD

Medicine (Pharmacology)

Drug resistance gene transfer; stem cell gene transfer; DNA repair and leukemogenesis

Edward Greenfield, PhD

Orthopaedics (Pathology)

Role of tyrosine kinase signaling tumerogenesis and metastasis of osteosarcoma

Clifford Harding, MD PhD

Pathology

Cell biology and immunology of MHC-I and II antigen processing

Michael Harris, PhD

Biochemistry

Mechanistic enzymology; RNA biophysics

Peter Harte, PhD

Genetics

Regulation of Homeotic gene expression during Drosophila development

Maria Hatzoglou, PhD

Nutrition (Biochemistry)

Post transcriptional regulation of stress response genes

Amy Hise, MD

Pathology

Activation and attenuation mechanisms in the innate immune response

Eckhard Jankowsky, PhD

RNA Center (Biochemistry)

Enzymology and biological function of RNA helicases

Hung-Ying Kao, PhD

Biochemistry

Regulation of gene expression by chromatin structure; role of tumor suppressors in leukemia

Jonathan Karn, PhD

Molecular Biology and Microbiology

Control of gene expression in HIV

Ruth Keri, PhD

Pharmacology

Molecular mechanisms of mammary gland development and breast cancer by reproductive hormones

Ahmad Khalil, PhD

RNA Center (Biochemistry)

Epigenetic regulation of gene expression by large non-coding RNAs

Thomas La Framboise, PhD

Proteomics Center (Genetics)

Development and application of computational tools to identify variations that contribute to disease

Andrea Ladd, PhD

CCF (Molecular Biology and Microbiology)

Pre-mRNA alternative splicing regulation in heart and muscle development

Gary Landreth, PhD

Neurosciences

Clearance of amyloid protein in Alzheimer’s disease; role of ERK  MAP kinase signaling in CNS development

Michael Lederman, MD

Medicine (Molecular Biology and Microbiology)

Molecular and cellular mechanisms of immune deficiency; Enhancing immune function in HIV-1 infection

Alan Levin, PhD

Medicine (Molecular Biology and Microbiology)

Molecular mechanisms of T-cell activation in mucosal immunity; HIV induced mucosal permeability

Donnie Licatalosi, PhD

RNA Center (Biochemistry)

Genome wide analysis of developmental gene regulation by RNA binding proteins

Hua Lou, PhD

Genetics

Regulation of alternative splicing in mammals

Sanford Markowitz, MD PhD

Medicine (Molecular Biology and Microbiology)

Role of genome instability in inherited and sporadic colon cancers

David McDonald, PhD

Molecular Biology and Microbiology

Visualization of intra- and intercellular trafficking of HIV

Robert Miller, PhD

Neurosciences

CNS neural development; biology of neurodegenerative diseases

Masaru Miyagi, PhD

Proteomics Center (Genetics)

Protein structure by chemical modification and  LC-MS; development of proteomic methods using tandem mass spectrometry

Monica Montano, PhD

Pharmacology

Estrogen control of breast cancer growth regulatory pathways

Timothy Nilsen, PhD

RNA Center (Biochemistry)

Mechanism of microRNA regulation of gene expression

Krzysztof Palczewski, PhD

Pharmacology

Protein structure and dynamics during phototransduction

Helen Salz, PhD

Genetics

Regulation of sex-specific pre-mRNA splicing in Drosophila

Peter Scacheri, PhD

Genetics

Transcriptional control of cellular pathways and identification of regulatory elements

Witold Surewicz, PhD

Physiology and Biophysics

Biophysics of amyloid protein folding diseases

Alan Tartakoff, PhD

Pathology

Cell biology of yeast cell division

Derek Taylor, PhD

Pharmacology

Cryo-electronmicroscopy and single particle reconstruction of macromolecular assemblies

Focco van den Akker, PhD

Biochemistry

Structural biology of guanylyl cyclases and beta-lactamase enzymes

Michael Weiss, MD PhD

Biochemistry

Transcriptional control of gene expression; protein folding and mis-folding

Patrick Wintrode, PhD

Physiology and Biophysics

Macromolecular structure and dynamics

Jo Ann Wise, PhD

Molecular Biology and Microbiology

Mitotic regulation of gene expression in yeast

Vivian Yee, PhD

Biochemistry

Structural Biology of biotin enzymes and prion proteins