CASE.EDU:    HOME | DIRECTORIES | SEARCH
case western reserve university

THE CENTER FOR GENETIC RESEARCH ETHICS & LAW

 

TRAINING

Post-Doctoral Fellowships


APPLICATIONS FOR FALL 2008 ARE DUE APRIL 1, 2008.

 

The CGREAL Post-doctoral program recruits trainees who are have demonstrated promise as researchers in interdisciplinary fields that are relevant to genetic research ethics and law and who can immediately benefit from didactic training and intensive mentorship. Its major goal is to train researchers whose work is focused on seeking answers to ethical, legal and social questions surrounding the design and conduct of human genetic research, and the development of sound ways to implement such answers in policy.

Because of the interdisciplinary nature of this research, it is often the case that individuals come to work on ELSI topics an idiosyncratic fashion. To remediate this, we offer a flexible 1-2 year training program to help guide young investigators to this field of study and to provide them with integrated but focused training. We targeted individuals for training who have received a doctorate in the social and behavioral sciences (i.e., sociology, psychology, anthropology), genetics or other basic sciences, nursing and medicine, law and the humanities.

The CGREAL Post-Doctoral Program is based in an experiential learning environment situated within mentored relationships. The current size of the program is quite modest; we take, on average, two new trainees per year and never more than three.

The training program consists of:

  1. An individualized longitudinal curriculum in ethics, genetics and the social sciences, offered through relevant academic departments and programs. Upon entry into the program, each trainee’s research and clinical training is evaluated to ascertain which ‘package’ of courses the trainee will take.
  2. Development of tailored genetic research ethics research experiences designed to expose trainees to a variety of research paradigms and disciplines.
  3. A mentored genetic research ethics research project designed and conducted by the trainee in collaboration with his/her mentors.


Early Mentorship Program
Trainees are assigned to a participating faculty mentor to orient and guide the trainee during their first months of fellowship. We attempt to match trainees with initial mentors who are likely to become the permanent primary mentor although trainees may revise their focus of interest. With their initial mentor’s help, trainees select a primary mentor and several other secondary mentors to form a multidisciplinary mentoring committee. The package of courses, seminars, and brief research rotations will prepare the trainee to conduct research on ethical, legal and social issues in genetic research.

Individualized Longitudinal Curriculum
One of the primary functions of the early mentorship program is to assist trainees to develop an individualized learning plan within the first two months of his/her entry into the program. This includes the selection of a research mentor, a research project and an outline of the courses and/or seminars that the trainee should pursue to supplement their prior doctoral training. Trainees may have adequate exposure to research methods but may lack the exposure to genetic concepts and research practices; physician and scientific trainees may need to supplement their genetic and clinical knowledge with research methodology, ethics, law, and the social sciences. In order to meet these different needs, a catalog of courses and seminars available throughout the university is provided to the trainee. The student, with the help of the initial mentor, then selects the courses/seminars needed to reach his/her specific training objectives.


Research Experience

The cardinal elements of the proposed training program are the research experiences and training offered to our trainees. For each trainee, we develop an individualized program that gives them training in a variety of content areas and methodologies. Trainees’ research projects should be concentrated within the four specific aims of the Center for Genetic Research Ethics and Law: 1) cultural meaning; 2) social values; 3) moral imagination and, 4) responsible policy.

 

Individual Candidate Training Plans

The development of the fellow’s research proposal and conducting the research project is the most important element of the training program. During the course of the individually tailored studies, the trainee identifies possible research projects and with the help of his or her primary mentor and mentoring committee, chooses a project and then identifies the theoretical, methodological, and clinical areas of expertise necessary to successfully carry out the research project. This includes subject recruitment or accessing the correct databases, data collection or handling of databases, and data analysis and manuscript development. Mentors come from a variety of disciplines and vary in number depending on the research plan. These faculty form the trainee’s mentoring group. .
As the trainee progresses through the varying stages of accomplishing the work, the committee continually assesses whether additional skills or knowledge bases need to be added. This focused skills training is designed to teach the trainee the skills needed to conduct their research through brief didactic work and hands-on learning. Trainees also have the opportunity to learn necessary quantitative skills in a similar fashion. The trainee is encouraged to continue making progress to work as independently as possible as his/her skills accrue.

 

Shared Resources

The CGREAL’s shared resource cores provide important enabling resources for the research programs and initiatives. These provide access to expertise and instrumentation that leverage research beyond what would be possible by individual investigators.

Mentors
Mentors are all Case faculty who represent researchers from a variety of disciplines including genetics, anthropology, bioethics, health law, sociology of science, health services research, and political science. They also include the clinical areas of medical genetics, oncology, genetic counseling, nursing and pediatrics. All of these mentors have committed to provide research experiences to trainees (whether brief or for their major project) and evaluate and develop the tailored training curriculum for their primary trainees. Within the first two months of the program, trainees will select a primary mentor who will then help them construct a mentoring committee. The committee members were chosen to meet the trainee’s needs for research mentorship and experiences, development of methodological expertise (research design and analysis), relevant content expertise, and professional development.

LIST OF MENTORS:

Mark Aulisio, PhD
Jessica Berg, JD
Robert Binstock, PhD
Dena Davis, PhD, JD
David Deeds, PhD
Jennifer Fishman, PhD
Atwood Gaines, PhD
Sharona Hoffman, JD
Eric Juengst, PhD
Eric Kodish, MD
Patricia Marshall, PhD
Anne Matthews, PhD
Maxwell Mehlman, JD
Joseph Nadeau, PhD
Stephen Post, PhD

Mary Quinn Griffin, PhD
Eric Topol, MD
Georgia Wiesner, MD
Chris Winkelman, PhD
Peter Whitehouse, MD, PhD
Nancy Wolf, PhD, MD
Stuart Youngner, MD

Peer Review Committee

The Peer Review Committee will meet biannually to review recruitment and selection of trainees, select research activities and mentors for trainees, approve graduate education programs, and evaluate trainee progress.

 

Selection Criteria

Acceptance of candidates will continue to be evaluated in terms of: 1) the candidate’s potential to become an independent investigator, 2) a match between candidate’s research interests and one of our four specific aims, 3) a match between the candidate’s training needs and our training expertise, and 4) a match between candidate’s research interests and needs and potential program mentors.

Selection Process and Recruitment

Candidates are required to submit the following set of documents by April 1 of the calendar year of expected enrollment in the training program: 1) a recent curriculum vitae including previous research experience, 2) a personal statement describing the reason for seeking research training and their specific interests in genetic research ethics, 3) one general letter of recommendation, and 4) letter of support from their training director or doctoral committee chairperson/advisor.

Our Peer Review Committee reviews all applications. The criteria used to judge applicants includes: 1) a commitment to a career in genetic research ethics in an academic or related environment and the estimated likelihood that participation in the training program will further this goal, 2) academic excellence, and 3) information from the letters of recommendation and evidence of ability to succeed as a researcher as evidenced through the submitted materials and interviews with faculty.


Minority Recruitment
Minority recruitment will be a high priority for this program. The Case School of Medicine has an outstanding track record in recruiting minority candidates.

Evaluation Plan

Assessment of Trainees' Progress
Progress of the trainees is evaluated by the Mentoring Committees at specified intervals during the course of their training. The goal of the Mentoring Committee's performance evaluation is to assess the trainee's performance in an individualized fashion that focuses on meeting the fellow's particular career development and research goals. The evaluation by the Peer Review Committee considers the individual fellow's program and the evaluation of the Mentoring Committee, but also focuses more generally on how well the performance measures are being met.

Guidance in Next Steps
This program serves as a springboard for participants' careers as ELSI researchers. Graduates are being prepared to successfully compete for funding via K07, K08, K23, R03, R01, or foundation grants. The goal is for CGREAL graduates to become independent but highly collaborative investigators working within the entire spectrum of relevant academic research.

Discussions between mentors and trainees about post-graduation placement are ongoing throughout the course of the program and the full range of opportunities available to graduates explored. Mentors cultivate networking and collaborative opportunities between trainees, extramural researchers, and others with whom long-term working relationships might be forged.