This Week in CGREAL Home * Genetics in the News * Genetics in the Literature * Archive
Center NewsEric Juengst will be serving as a Visiting Professor in the Program on Ethics and the Life Sciences at the University of Newcastle for the next two weeks, to work with External Advisory Board member Erica Haimes on issues in genetics and identity. A symposium organized by Patty Marshall, "Progress in Human Genetics Research in Africa: Science, Technology, and Ethics," was accepted for the AAAS meeting in February 2008. Panelists include researchers from the U.S., Kenya, Nigeria, and South Africa. Nicholas King Shlomit Zuckerman ("Expansion of Newborn External Advisory Board member Richard Sharp has relocated to the Cleveland Clinic as Director of Bioethics Research. The 2007 CGREAL Annual Retreat will be Friday, November 2, 2007 at Squire Valleevue Farm. Save the Date! May 1-3, 2008 Please distribute the attached flyer! OpportunitiesCall for Abstracts Pharmacogenomics (Joint CSHL/Wellcome Trust Conference Call for Abstracts 2007 Annual HRPP Conference | PRIM&R Realizing Personalized Medicine Through Genomics August 20-21 U of New England Call for Papers: Testing genes, profiling DNA: The global governance of genomics - hopes, duties and security ESF-ORI First World Conference on Research Integrity: Fostering Responsible Research September 16-19 Eyes on the Prize: Truth Telling about Genetic Testing NE Ohio ACRP: Promoting Excellence in Clinical Research Conference The all-day conference will focus on compliance with speakers representing the FDA, OHRP, and internal compliance departments from various institutions and would benefit investigators, research coordinators, monitors, IRB members, and other personnel who participate on the research team. Health Policy Research FELLOWSHIP Call for Papers: Testing genes, profiling DNA: The global governance of genomics - hopes, duties and security 3rd Annual Corsage Workshop: Contingencies of Genomics - Finding Roads into the Future Utrecht, Netherlands Due 6 November One Origin, One Race, One Earth: Genetics, Human Rights and the Next Phase of Human Evolution Netherlands Genomics Initiative: Genomics Momentum 2007 Annual HRPP Conference | PRIM&R 3rd Annual Corsage Workshop: Contingencies of Genomics - Finding Roads into the Future 13 December, 2007 Utrecht, Netherlands What's The Use of Race? Translating “ELSI”: International Congress on
Please contact Eric Juengst if you are submitting an abstract or are interested in a coordinated CGREAL submission. Resources
Centers for Excellence in ELSI Research (CEER)
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Genetics in the News
Suspended Gene Therapy Test Had Drawn Early Questions (Washington Post) "Some also expressed concern that the informed consent document the researchers planned to use to describe the risks and benefits to participating patients was not upfront enough about the fact that the study was unlikely to help them and was designed merely to test the new approach's safety. ..."
The Chronicle of Higher Education "It is time to exempt such low-risk studies from federal regulation. ..."
A South Carolina biotech firm re-engineers trees - Aug. 1, 2007 "A South Carolina biotech firm re-engineers trees to make them grow faster and cleaner ..."
Designer-baby rules 'should be relaxed to save more siblings' - Independent Online Edition > UK Politics "They want scientists to be able to use tissue matching and embryo selection if it can help a sibling with a condition that is serious but not immediately likely to prove fatal such as sickle-cell anaemia. ..."
First new multiple sclerosis gene found in 30 years "A newly identified gene may hold the promise of guiding future research into therapies for multiple sclerosis in what its discoverers say is the first major genetic advance in 30 years for understanding this nervous system disease. ..."
Study: Genes Influence How We Choose Friends - Newsweek Health - MSNBC.com "A new study says that how we choose our friends is strongly influenced by genetic factors. ..."
Black Death casts a genetic shadow over England - - New Scientist "plagues known as the Black Death killed so many people in the Middle Ages that, to this day, genetic diversity is lower in England than it was in the 11th century, according to a new analysis. ..."
The Scientist : The Perils of Industrialization "How the industrialization of academic science has ruined research, and what we can do about it. ..."
The Genetic Genealogist - » The Personal Genome Project s First 10"the first ten volunteers of the Personal Genome Project, announced today: ..."
FDA Drug Standards: What's Safe Enough? "Why would the FDA allow a pharmaceutical company to continue to sell an apparently dangerous drug? The answer is not simple, and at a time when mistrust of the government's relationship with the healthcare industry seems to be increasing, the subtleties can get lost in daily news reports. ..."
Why Africa Fears Western Medicine (New York Times)
Descendants of Dolly (Guardian "Scientists will have to work hard to persuade a cynical public to tuck in to the idea of cloned meat ..."
Emotional recall is in your genes - - New Scientist "Your ability to recall emotional events such as meeting the love of your life, or the trauma of a painful car crash is governed by a common variation in a single gene, according to a new study. ..." [Related: Neuroscience and genetics | Lest we forget or lest we remember? (Economist)"More Swiss than Rwandans have a gene for unusually good emotional memory ..."]
Duplicate genes help humans go the extra mile (New Scientist)"that helps supply our cells with energy, a new study suggests. That supports the idea that endurance running gave our human ancestors an evolutionary edge. ..."
Single gene deletion boosts lifespan (Nature)"Mutant mice live longer, age slower and eat more. ..." [Related: Longevity Pill Tested in Humans "Sirtris Pharmaceuticals announces that its souped-up version of resveratrol has passed early tests in humans. ..."]
Genetics in the Literature
(2007). "Board games." Nature 448(7153): 511-512. "The way research on human subjects is overseen in the United States requires reform. ..."
(2007). "No faulty-gene carrier need apply." Nat Meth 4(8): 597-597. "Consistent laws against genetic discrimination are needed to allow the development of genomic medicine and ensure individual participation in genetic research. ..."
(2007). "A sporting chance." Nature 448(7153): 512-512. "Bans on drug enhancement in sport may go the way of earlier prohibitions on women and remuneration. ..."
Arking, R. (2007). "Human Reproductive Costs and the Predicted Response to Dietary Restriction." Rejuvenation Res. "A review of the pertinent literature suggests that these three models, while plausible, are not capable of making robust predictions that are consistent with human data not used in their development. Given this weakness, none of the predictions made by these theories should be relied on for policy development at this time. If the human cultural pro-longevity practices can be quantified in terms of their effect on energy allocation, then this model may serve in future as a realistic quantitative model capable of identifying pertinent pathways and making robust predictions. ..."
Karlan, B. Y., A. Berchuck, et al. (2007). "The Role of Genetic Testing for Cancer Susceptibility in Gynecologic Practice." Obstet Gynecol 110(1): 155-167. "The subsequent clinical recommendations for mutation carriers need to take into account the patient's age, desire for future childbearing, and other medical history when prescribing screening interventions or prophylactic surgery. Practical applications of genetic testing for cancer susceptibility have the ability to reduce the burden of hereditary cancers by saving lives, decreasing medical morbidities, and reducing psychological stress. ..."
Lartigue, C., J. I. Glass, et al. (2007). "Genome Transplantation in Bacteria: Changing One Species to Another." Science 317(5838): 632-638. "As a step toward propagation of synthetic genomes, we completely replaced the genome of a bacterial cell with one from another species by transplanting a whole genome as naked DNA. . ..."
Ledford, H. (2007). "Human-subjects research: Trial and error." Nature 448(7153): 530-532. "The ethics committees that oversee research done in humans have been attacked from all sides. Heidi Ledford recounts the struggle to come up with alternatives. ..."
Molnar, M. J. and P. Bencsik (2006). "Establishing a Neurological-Psychiatric Biobank: Banking, informatics, ethics." Cellular Immunology 244(2): 101-104. "The goal is to establish nationwide collaboration and common biobanking standards on quality, access, and protection of integrity in the field of neurology and psychiatry. ..."
Roland, M.-C. (2007). "Who is responsible? Supervisors and institutions need to focus on training in the responsible conduct of research and change the culture in the laboratory." EMBO Rep. 8(8): 706-711. "The attitudes, beliefs and behaviour of researchers who are responsible for training students need to change to reduce the mismatch between training in the research environment and the expectations of society ..."
Weksberg, R., C. Shuman, et al. (2007). "Workshop report: evaluation of genetic and epigenetic risks associated with assisted reproductive technologies and infertility." Fertility and Sterility 88(1): 27-31. "In January 2005, the Assisted Reproductive Technologies (ART) Workshop: Evaluation of Genetic and Epigenetic Risks Associated with Assisted Reproductive Technologies and Infertility was convened to evaluate current data on genetic and epigenetic risks to offspring conceived after a period of infertility and/or via ARTs. ..."
Stewart, A., P. Brice, et al. (2007). Genetics, Health Care and Public Policy: An Introduction to Public Health Genetics, Cambridge University Press."Genetics, Health Care and Public Policy is an introduction to the new discipline of public health genetics. It brings together the insights of genetic and molecular science as a means of protecting and improving the health of the population. This book sets out the basic principles of public health genetics for a wide audience of readers from those providing health care to those involved in establishing health policy. It provides one-stop introductory coverage of this rapidly developing and multidisciplinary field. ..."
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