| Publications | |
| Yang Q, The DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases. Nat Struct Mol Biol. 13, 981-6 (2006) |
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Highlighted in: Editor's Choice, Science, 314, 1219 (2006) News and Views, Nat Struct Mol Biol. 13, 954-5 (2006) |
| Bowers H, Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases. (Review) Nucleic Acids Res. 34, 4181-8 (2006) |
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| Beran RK, Bruno MM, Bowers HA, , Pyle AM Robust translocation along a molecular monorail: the NS3 helicase from hepatitis C virus traverses unusually large disruptions in its track. J Mol Biol. 358, 974-82 (2006) |
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| Bowers HA, Maroney PA, Fairman ME, Kastner B, Lührmann R, Timothy W. Nilsen TW & Discriminatory RNP remodeling by the DEAD-box protein DED1. RNA 12, 903-912 (2006) |
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| Beran RK, Bruno MM, Bowers HA, & Pyle AM Robust translocation along a molecular monorail: the NS3 helicase from hepatitis C virus traverses unusually large disruptions in its track. J. Mol. Biol. 358, 974-982 (2006) |
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| , Fairman ME & Yang, Q RNA helicases: versatile ATP-driven nanomotors. (Review) J. Nanosci. Nanotechnol. 5, 1983-1989 (2005) |
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Helicase snaps back. (News and Views) Nature 437, 1245 (2005) |
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| Yang Q & ATP- and ADP-dependent modulation of RNA unwinding and strand annealing activities by the DEAD-box protein DED1. Biochemistry 44, 13591-1601 (2005) |
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| Bordeleau ME, Matthews J, Wojnar JM, Lindqvist L, Novac O, , Sonenberg N, Northcote P, Teesdale-Spittle P & Pelletier J. Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation. Proc. Natl. Acad. Sci USA 102, 10460-10465 (2005) |
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| Fairman M, Maroney P, Wang W, Bowers H, Gollnick P, Nilsen,
TW & : Protein displacement by DExH/D "RNA helicases" without duplex unwinding. Science 304, 730-734 (2004) |
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Highlighted in: Perspective, Science 304: 694-695 (2004) News and Views, Nature Struct. Mol. Biology 11, 494 - 496 (2004) |
| Kawaoka J, & Pyle AM: Backbone tracking by the SF2 RNA helicase NPH-II. Nature Structural & Molecular Biology 11, 526-530 (2004) |
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Highlighted in: News and Views, Nature Struct. Mol. Biology 11, 494 - 496 (2004) |
| Pang PS, , Planet PJ & Pyle AM: The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding. EMBO J. 21, 1168-1176 (2002) |
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| Kang DC, Gopalkrishnan RV, Wu Q, , Pyle AM &
Fisher PB: Mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties. Proc. Natl. Acad. Sci. USA 99, 637-642 (2002) |
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Highlighted in: Editor's choice, Science 295, 5558 (2002) |
| , Gross CH, Shuman S, & Pyle
AM: Active disruption of an RNA-protein interaction by a DExH/D RNA helicase. Science 291, 121-125 (2001) |
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Highlighted in: Research Update, Trends Biochem. Sci. 26, 339-341 (2001) Perspective, Science 291, 1916-1917 (2001) Specific Review, Nature Struct. Biol. 8,113-116 (2001) |
| , Gross CH, Shuman S, & Pyle AM: The DExH protein NPH-II is a processive and directional motor for unwinding RNA. Nature 403, 447-451 (2000). |
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Highlighted in: News and Views, Nature Struct. Biol. 7, 97-99 (2000) |
| Pyle AM, Chu VT, & Boudvillain M: Using DNAzymes to cut, process, and map RNA molecules for structural studies or modification. Methods Enzymol. 317, 140-146 (2000) |
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| & Jankowsky A: The DExH/D protein family database. Nucleic Acids Res. 28, 333-334 (2000) |
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| Wagner JD, , Company M, Pyle AM & Abelson
JN: The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes. EMBO J. 17, 2926-2937 (1998) |
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| & Schwenzer B: Oligonucleotide facilitators enable a hammerhead ribozyme to cleave long RNA substrates with multiple-turnover activity. Eur J Biochem. 254, 129-134 (1998) |
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| , Strunk G & Schwenzer B: Peptide nucleic acid (PNA) is capable of enhancing hammerhead ribozyme activity with long but not with short RNA substrates. Nucleic Acids Res. 25, 2690-2693 (1997) |
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| & Schwenzer B: Efficient improvement of hammerhead ribozyme mediated cleavage of long substrates by oligonucleotide facilitators. Biochemistry 35, 15313-15321 (1996) |
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| & Schwenzer B: Oligonucleotide facilitators may inhibit or activate a hammerhead ribozyme. Nucleic Acids Res. 24, 423-429 (1996) |
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