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						|  Fresh Muscle Biopsies at Cleveland, OH  |  
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						 Below are assays that can be ordered when a fresh muscle biopsy is done in Cleveland, Ohio.  For a comprehensive list that includes CPT codes and costs see 
						Test and Price List for On-Site Muscle Biopsy Studies.
                                                                         
                         
                          
                            | Test | Method Description | CPT Code |  
                            | 
                              Adenine Nucleotide Translocase | Spectrophotometric enzyme assays | 84999  |    
                          
                            | Test | Method Description | CPT Code |  
                            | Carnitine Palmitoyltransferases (I & II)  | Three radioactive enzyme assays of total CPT activity: (1) forward direction, (2) reverse reaction, and (3) malonyl-CoA sensitive activity, forward reaction | 84999 |    
                          
                            | Test | Method Description | CPT Codes |  
                            | 
                              Electron Transport Chain (Complexes I-IV) | Spectrophotometric enzyme assays: cytochrome c reduction with NADH + rotenone (I + III), succinate + antimycin (II +III), decylubiquinol + antimycin (III), oxidation of reduced cytochrome c (IV)  | 84999 82657 84157 80502 |    
                          
                            | Test | Method Description | CPT Codes |  
                            | Fatty Acid Oxidation Enzymes | 
                            Spectrophotometric enzyme
                            assays with chain-length
                            specific substrates 
                            (intermediates of b-oxidation) | 84999 82657 84157 80502 |    
                          
                            | Test | Method Description | CPT Codes |  
                            | a-Ketoglutarate Dehydrogenase Complex | Radioactive enzyme assay | 
                              84999, 82657 84157, 80502 |    
                          
                            | Test | Method Description | CPT Code |  
                            | 
                              
                                Krebs cycle enzymes *Aconitase *Fumarase *Glutamate Dehydrogenase *Isocitrate Dehydrogenase *Malate Dehydrogenase *Succinate Dehydrogenase | Spectrophotometric or radioactive enzyme assays | 84999  |    
                          
                            | Test | Method Description | CPT Code |  
                            | Oxidative Phosphorylation | Isolation of mitochondria from fresh tissue with assays of oxidative phosphorylation using multiple substrates to study overall mitochondrial function | 84999 |    
                          
                            | Test | Method Description | CPT Codes |  
                            | Pyruvate Dehydrogenase Complex | Radioactive enzyme assay by 1-14C-pyruvate decarboxylation (includes components if overall activity low) and dihydrolipoamide dehydrogenase | 84999 82657 84157 80502 |      Return to TESTS 
					    					 					   
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