The primary goal of the Cardiovascular Physiology and Phenotype Lab is to generate state-of-art disease models and phenotype discovery for basic and translational medicine research. A lot of reliable disease models related to cardiovascular system, urinary system and central nervous system have been established. These models include, but are not limited to, TAC (Transverse Aortic Constriction), myocardial infarction, myocardial ischemia/reperfusion injury, heart failure, limb ischemia, MCAO (Middle Cerebral Artery Occlusion), kidney ischemia/reperfusion injury, deep vein thrombosis. High definition echocardiography, hemodynamic technic and telemetric transmitter implantation is also used to discover the phenotype of gene engineered mice.
Cardiovascular Physiology and Phenotype Lab has been closely collaborating with the investigators from Case Cardiovascular Research Institute, Institute for Transformative Molecular Medicine and Harrington Heart & Vascular Institute, and helps together researchers of multiple disciplines to link genes to function in the whole animal level.
Cardiovascular Physiology and
Case Cardiovascular Research Institute
Institute for Transformative