| Date | Location | Result | |
| Apr 24, 2006 | Alliance, OH | Mount Union College 4, Case Western Reserve 1 | Box score |
| Apr 24, 2006 | Alliance, OH | Mount Union College 8, Case Western Reserve 0 | Box score |
| Apr 20, 2006 | Cleveland, OH | Baldwin-Wallace Coll 7, Case Western Reserve 3 | Box score |
| Apr 20, 2006 | Cleveland, OH | Case Western Reserve 5, Baldwin-Wallace Coll 3 | Box score |
| Apr 18, 2006 | Cleveland, OH | Notre Dame College 5, Case Western Reserve 2 | Box score |
| Apr 18, 2006 | Cleveland, OH | Notre Dame College 3, Case Western Reserve 1 | Box score |
| Apr 13, 2006 | Granville, OH | Case Western Reserve 1, Denison University 0 | Box score |
| Apr 13, 2006 | Granville, OH | Denison University 4, Case Western Reserve 1 | Box score |
| Apr 10, 2006 | University Hts., OH | John Carroll Univ. 1, Case Western Reserve 0 | Box score |
| Apr 10, 2006 | University Hts., OH | Case Western Reserve 4, John Carroll Univ. 3 | Box score |
| Apr 09, 2006 | Albion, MI | Case Western Reserve 7, Albion College 3 | Box score |
| Apr 09, 2006 | Albion, MI | Case Western Reserve 3, Albion College 0 | Box score |
| Apr 08, 2006 | Grand Rapids, MI | Case Softball 2, Calvin College 1 | Box score |
| Apr 08, 2006 | Grand Rapids, MI | Calvin College 6, Case Western Reserve 1 | Box score |
| Apr 06, 2006 | Cleveland, OH | Bethany College 6, Case Softball 1 | Box score |
| Apr 06, 2006 | Cleveland, OH | Case Softball 5, Bethany College 4 | Box score |
| Apr 02, 2006 | Cleveland, OH | Case Softball 5, Westminster College 4 | Box score |
| Apr 02, 2006 | Cleveland, OH | Case Softball 5, Westminster College 1 | Box score |
| Apr 01, 2006 | Cleveland, OH | Allegheny College 5, Case Softball 0 | Box score |
| Apr 01, 2006 | Cleveland, OH | Case Softball 2, Allegheny College 1 | Box score |
| Mar 29, 2006 | Cleveland, OH | Otterbein College 7, Case Softball 4 | Box score |
| Mar 29, 2006 | Cleveland, OH | Otterbein College 3, Case Softball 2 | Box score |
| Mar 26, 2006 | Gambier, OH | Case Western Reserve 1, Kenyon College 0 | Box score |
| Mar 26, 2006 | Gambier, OH | Kenyon College 1, Case Western Reserve 0 | Box score |
| Mar 25, 2006 | Cleveland, OH | Case Softball 11, Bluffton University 10 | Box score |
| Mar 23, 2006 | Painesville, OH | Case Softball 1, Lake Erie College 1 | Box score |
| Mar 23, 2006 | Painesville, OH | Lake Erie College 5, Case Softball 3 | Box score |
| Mar 18, 2006 | Altamonte Springs,FL | Washington Univ. 10, Case Western Reserve 2 | Box score |
| Mar 17, 2006 | Altamonte Springs,FL | Brandeis University 7, Case Western Reserve 1 | Box score |
| Mar 17, 2006 | Altamonte Springs,FL | Univ. of Rochester 3, Case Western Reserve 1 | Box score |
| Mar 16, 2006 | Altamonte Springs,FL | Emory University 6, Case Western Reserve 0 | Box score |
| Mar 15, 2006 | Altamonte Springs,FL | Washington Univ. 8, Case Western Reserve 0 | Box score |
| Mar 15, 2006 | Altamonte Springs,FL | Brandeis University 6, Case Western Reserve 2 | Box score |
| Mar 14, 2006 | Altamonte Springs,FL | Univ. of Rochester 3, Case Western Reserve 0 | Box score |
| Mar 14, 2006 | Altamonte Springs,FL | Emory University 8, Case Western Reserve 0 | Box score |
| Mar 12, 2006 | Cocoa Beach, FL | Case Softball 1, Ripon College 0 | Box score |
| Mar 12, 2006 | Cocoa Beach, FL | Case Softball 3, Ripon College 2 | Box score |
| Mar 11, 2006 | Cocoa Expo | Case Softball 3, WPI Softball 0 | Box score |
| Mar 11, 2006 | Cocoa Expo | Case Softball 7, Wheelock College 4 | Box score |