Department of Chemistry

Graduate Chemistry Courses

Course Credits Description
CHEM 406: Chemical Kinetics 3 Theory and characterization of chemical rate processes. Recommended preparation: Two semesters of undergraduate physical chemistry.
CHEM 407:Chemical Thermodynamics 3 Thermodynamics and statistical thermodynamics and their application to chemical problems. Recommended preparation: Two semesters of undergraduate physical chemistry.
CHEM 408: Advanced Physical Chemistry 3 Topics in physical chemistry, intended for entering graduate students, giving background tools appropriate for graduate research in areas of chemistry other than physical chemistry. Illustrations from the contemporary chemical research literature will be emphasized. Thermodynamics and statistical mechanics, quantum chemistry and computation, spectroscopy, and chemical kinetics and dynamics. Recommended preparation: One year of undergraduate physical chemistry.
CHEM 410: Instrumental Analytical Chemistry 3 Principles and applications of analytical instrumentation including optical spectroscopy, photoelectron and ion bombardment spectrometry, NMR and magnetic resonance imaging.
CHEM 412: Advanced Inorganic Chemistry I 3 Chemistry of inorganic systems, with emphasis on spectroscopy, magnetism, and stereochemistry of transition metal compounds.
CHEM 413: Advanced Inorganic Chemistry II 3 Chemistry of inorganic compounds, with special emphasis on mechanisms of reactions.

CHEM 414: Organometallic Reactions and Structures

3 Developments in the understanding of bonding and structure in organometallic chemistry and the relevance of organometallic species to chemical catalysis.
CHEM 415: Principles of Instrumental Analysis 3 A one semester lecture course in chemical instrumentation including measurement basics, atomic and molecular spectroscopy, electroanalytical chemistry, and separation methods. Offered as CHEM 315 and CHEM 415.
CHEM 417: Radiochemistry 3 Radio activity and its applications, beginning with basic theory and techniques and extending through applications in chemistry, biology, engineering, and medicine.
CHEM 421: Advanced Organic Chemistry I 3 Elementary general molecular orbital theory. Stereoisomerism. Reaction mechanisms. Pericyclic reactions and orbital symmetry conservation. Organic photochemistry. Free radical, radical ion, carbene, nitrene, aryne intermediates and their reactions.
CHEM 422: Advanced Organic Chemistry II 3 Carbocations and carbanions. Nucleophilic and electrophilic aliphatic substitutions. Heterolytic addition and elimination reactions. Electrophilic, nucleophilic, and free radical aromatic substitutions. Carbonyl reactions. Oxidations, reductions, rearrangements.
CHEM 425: Physical Methods for Determining Organic Structure 3 Lectures on determination of structure of organic compounds involving separation techniques and the application of infrared, ultraviolet and visible spectroscopy, nuclear magnetic resonance spectroscopy, mass spectometry, and other modern instrumental techniques.
CHEM 428: Introductory Biochemistry 3 A survey of biochemistry with a strong emphasis on the chemical logic underlying metabolic pathways and the evolution of biomolecules. Cellular architecture. Amino acids and protein structure, purification, analysis, and synthesis. DNA, RNA, the flow of genetic information, and molecular biological technology. Enzyme kinetics, catalytic, and regulatory strategies. Sugars, complex carbohydrates, and glycoproteins. Lipids and cell membranes. Glycolysis, gluconeogenesis, carbon fixation through the "dark reactions" of photosynthesis, aerobic catabolism through the citric acid cycle, and glycogen metabolism. Biosynthesis and degradation of fatty acids, amino acids, and proteins. Offered as CHEM 328 and CHEM 428.
CHEM 429: Chemical Aspects of Living Systems 3 A series of special topics in the chemistry of biological processes at the level of molecular mechanisms. Chemical-biological interactions. Homogeneous catalysis in biochemical and biomimetic systems. Biochemical dynamics. Mitochondrial respiration and photosynthesis. Biological activity and carcinogenesis.
CHEM 430: Advanced Methods in Structural Biology 1-6 The course is designed for graduate students who will be focusing on one or more methods of structural biology in their thesis project. This course is divided into 3-6 sections (depending on demand). The topics offered will include X-ray crystallography, nuclear magnetic resonance spectroscopy, optical spectroscopy, mass spectrometry, cryo-electron microscopy, and computational and design methods. Students can select one or more modules. Modules will be scheduled so that students can take all the offered modules in one semester. Each section is given in 5 weeks and is worth 1 credit. Each section covers one area of structural biology at an advanced level such that the student is prepared for graduate level research in that topic. Offered as BIOC 430, CHEM 430, PHOL 430, and PHRM 430.
CHEM 433: Medicinal Chemistry and Drug Development 3 This course provides an overview on how principles in chemistry and biology are integrated to facilitate drug development. Primary emphasis will be placed on the development of organic molecules as drugs and metabolic enzymes as drug targets. Subjects pertinent to the introduction of medicinal chemistry, evaluation of drug efficacies in vitro and in vivo, and drug metabolism will be covered. Offered as CHEM 333 and CHEM 433.
CHEM 435: Synthetic Methods in Organic Chemistry 3 This course is designed to give students a practical knowledge of reactions and tactics that are currently used for organic synthesis. The use of tactical combinations of reactions is also covered.
CHEM 436: Complex Molecular Synthesis 3 The goal of this course is to provide an appreciation of the logic and strategical issues associated with modern organic synthesis. This is accomplished via in-depth analyses of notable syntheses drawn from the literature.
CHEM 439: Bioinorganic Chemistry 3 An introduction to metal ions in biology and medicine. Topics of emphasis include metalloenzymes, inorganic elements in pharmaceuticals, and physical methods of characterization in biology. Course material will be presented through a seminar format, and will involve extensive class participation, student presentations, and literature research reports. Offered as CHEM 339 and CHEM 439.
Prereq: Graduate standing.
CHEM 440: Solar Energy Conversion 3 This is a multidisciplinary course from a chemist's point of view. This course teaches the background necessary to read and understand the scientific literature on solar energy conversion, and includes some basic device physics, materials chemistry and chemistry. Topics provide an overview of the field and includes: Global energy perspective, principles of photovoltaics, crystalline solar cells, thin-film solar cells, dye-sensitized solar cells, organic solar cells (with emphasis on polymer-based solar cells), photoelectrochemical cells and artificial photosynthesis for fuel production, and semiconductor nanostructures and quantum dots for solar energy conversion. The course includes three laboratories and a demo using state-of-the-art equipment, as well as presentations of recent research articles by the graduate students. It is recommended that students have experience with thermodynamics. The following CWRU courses would meet this expectation: CHEM 301, CHEM 335, ENGR 225 or PHYS 313. Offered as CHEM 340 and CHEM 440.
CHEM 441: Functional Nanomaterials 3 This course is designed to introduce important concepts on the fundamental physical and chemical properties of technologically important nanometer scale materials. The course will cover an overview of the scientific principles pertaining to new properties at the nanoscale; synthesis and characterization tools; and existing and emerging applications of nanomaterials. It will center on current research developments on major classes of functional nanomaterials, including plasmonic nanoparticles, quantum dots, nanomagnets, carbon nanotubes, nanocatalysts and hybrid inorganic/organic nanostructures. In addition an emphasis will be placed on understanding the broader societal, economical and environmental impact of the scientific and technological advances brought forward by nanotechnology.
CHEM 445: Electrochemistry 3 Basic electrochemical properties of electrode-electrolyte interfaces and processes occurring thereat. Fundamental background for work in corrosion, electrodeposition, industrial electrolysis, electro-organic, batteries, fuel cells, and photoelectrochemical energy conversion.
CHEM 446: Quantum Mechanics I 3 Physical and mathematical foundations of quantum mechanics, including approximation methods and Hartree-Fock theory and time-dependent systems; application to problems in atomic and molecular structure and spectroscopy.
CHEM 447: Quantum Mechanics II 3 (Continuation of CHEM 446.) Ab initio, semi-empirical methods, configuration interaction, time-dependent phenomena, and principles of group theory.
CHEM 448: Statistical Mechanics 3 Systematic development of equilibrium statistical mechanics with emphasis on the properties of the gaseous, liquid, and solid states of matter. Introduction to non-equilibrium statistical mechanics.
CHEM 450: Molecular Spectroscopy 3 Rotation, vibration, and electronic spectra of simple and complex molecules.
CHEM 460: NMR Spectroscopy and Imaging 3 Fundamental and advanced topics in understanding and practice of NMR imaging and spectroscopy. Theoretical description is accompanied by specific examples of spin Hamiltonians, pulse sequences, and basic instrumentation.
CHEM 475: Protein Biophysics 3 This course focuses on in-depth understanding of the molecular biophysics of proteins. Structural, thermodynamic and kinetic aspects of protein function and structure-function relationships will be considered at the advanced conceptual level. The application of these theoretical frameworks will be illustrated with examples from the literature and integration of biophysical knowledge with description at the cellular and systems level. The format consists of lectures, problem sets, and student presentations. A special emphasis will be placed on discussion of original publications. Offered as BIOC 475, CHEM 475, PHOL 475, PHRM 475, and NEUR 475.
CHEM 491: Modern Chemistry for Innovation I 3 The first half of a two-semester sequence providing an understanding of chemistry as a basis for successfully launching new high-tech ventures. The course will examine physical limitations to present technologies and the use of chemistry to identify potential opportunities for new venture creation. The course will provide experience in using chemistry for both identification of incremental improvements and as the basis for alternative technologies. Case studies will be used to illustrate recent commercially successful (and unsuccessful) venture creation and will illustrate characteristics for success. Admission to this course requires consent of the department.
CHEM 492: Modern Chemistry for Innovation II 3 Continuation of CHEM 491, with an emphasis on current and prospective opportunities for Chemistry Entrepreneurship. Longer term opportunities for Chemistry Entrepreneurship in emerging areas, including (but not be limited to) biomaterials, pharmacogenomics, biocatalysis, and drug discovery.
Prereq: CHEM 491.
CHEM 493: Feasibility and Technology Analysis 3 This course provides the tools scientists need to determine whether a technology is ready for commercialization. These tools include (but are not limited to): financial analysis, market analysis, industry analysis, technology analysis, intellectual property protection, the entrepreneurial process and culture, an introduction to entrepreneurial strategy and new venture financing. Deliverables will include a technology feasibility analysis on a possible application in the student's scientific area. Offered as BIOL 493, CHEM 493, and PHYS 493.
CHEM 501, 502: Special Topics in Inorganic Chemistry 1-6 Lectures on advanced topics in inorganic chemistry by staff or visiting lecturers. Course title, content, and number of credits vary from year to year.
CHEM 503, 504: Special Topics in Organic Chemistry 1-6 Lectures on advanced topics in organic chemistry by staff or visiting lecturers. Course title, content, and number of credits vary from year to year.
CHEM 505, 506: Special Topics in Physical Chemistry 1-6 Lectures on advanced topics in physical chemistry by staff or visiting lecturers. Course title, content, and number of credits vary from year to year.
CHEM 507, 508: Special Readings in Chemistry 1-6 Detailed study of a special topic in chemistry under the guidance of a faculty member. Maximum credit of 6 hours.
CHEM 509: Special Topics in Analytical Chemistry 1-6  
CHEM 511: Electrochemistry II 3 Electrocatalysis, semiconductor electrochemistry and photoelectrochemistry, and electrochemical impedance methods, as well as battery and fuel cell systems.
CHEM 601: Research Credit as arranged
Special research in an area of chemistry under the guidance of a faculty member.
CHEM 605: Chemistry Colloquium Series
1 Course content provided by weekly regular Department of Chemistry colloquia or Frontiers in Chemistry lectures. Discussion sessions provide review and discussion of previous lectures and lay foundation for forthcoming lectures.
CHEM 651: Masters Thesis (M.S.) 3 Credit as arranged
CHEM 701: Dissertation (Ph.D.) 1 Credit as arranged