garner research group

Publications

Article titles are linked to their full text in PDF format, located at OhioLINK (available to CWRU community and other participating institutions) or at the ACS Journal Archives.

• Garner, P.; Hu, J.; Parker, C. J.; Youngs, W. J.; Medvetz, D. “The Cu^I Catalyzed Exo-Selective Asymmetric Multicomponent [C+NC+CC] Reaction” Tetrahedron Lett. In press.
• Dogan, O.; Koyuncu, H.; Garner, P.; Bulut, A.; Youngs, W. J.; Panzner, M. “New Zinc(II)-Based Catalyst for Asymmetric Azomethine Ylide Cycloaddition Reactions” Org. Lett. 2006, 8, 4687.
• Garner, P.; Kaniskan, H. Ü.; Hu, J.; Youngs, W. J.; Panzner, M. “Asymmetric Multicomponent [C+NC+CC] Synthesis of Highly Functionalized Pyrrolidines Catalyzed by Silver(I)” Org. Lett. 2006, 8, 3647.
• Garner, P.; Sesenoglu, Ö.; Kaniskan, H. Ü. “S-(2-Pyrimidinyl)- and S-(2-(4,6-dimethylpyrimidinyl))-1,1,3,3- tetramethylthiouronium hexafluorophosphates: novel reagents for in situ peptide coupling” Tetrahedron Lett. 2006, 47, 483.
• Garner, P.; Kaniskan, H. Ü. “Synthesis of Highly Functionalized Pyrrolidines via a Mild One-Pot, Three-Component 1,3-Dipolar Cycloaddition Process” J. Org. Chem. 2005, 70, 10868.
• Garner, P.; Kaniskan, Ü. “A stereodivergent cascade imine → azomethine ylide → 1,3-dipolar cycloadditive approach to α-chiral pyrrolidines" Tetrahedron Lett. 2005, 46, 5181.
• Garner, P.; Sesenoglu, Ö. “3-Fluoro-6-tert-butyltetrahydropyranosyl Trichloroacetamidates. "Chiral Auxiliary Donors" for Hydroxyalkyl Radicals” Org. Lett. 2004, 6, 1217.
• Garner, P.; Dey, S.; Huang, Y. “α-Helical Peptide Nucleic Acid (αPNA)” In Pseudo-peptides in Drug Discovery, Nielsen, P. E., Ed.; Wiley-VCH: Weinheim, Germany, 2004; 193. (INVITED)
• Huang, Y.; Dey, S.; Zhang, X.; Sonnichsen, F.; Garner, P. “The α-Helical Peptide Nucleic Acid Concept: Merger of Peptide Secondary Structure and Codified Nucleic Acid Recognition” J. Am. Chem. Soc. 2004, 126, 4626.
• Garner, P.; Sesenoglu, Ö.; Burgoon, H. “A Camphor-Derived Chiral Auxiliary for Hydroxyalkyl Radicals” Tetrahedron: Asymmetry 2003, 14, 2883. (INVITED)
• Scardovi, N.; Garner, P. P.; Protasiewicz, J. D. “S-(2-Pyridinyl)-1,1,3,3-Tetramethylthiouronium Hexafluorophosphate. A New Reagent for the Synthesis of 2-Pyridinethiol Esters” Org. Lett 2003, 5, 1633.
• Huang, Y.; Dey, S.; Garner, P. “Trimethylsilyl Deriviatives of N⁴-Boc-Cytosine and I₂ -Mediated Nucleosidation of O-MTM Ethers” Tetrahedron Lett. 2003, 44, 1441.
• Garner, P.; Anderson, J. T.; Cox, P. B.; Klippenstein, S. J.; Leslie, R.; Scardovi, N. “Development of an Effective Chiral Auxiliary for Hydroxyalkyl Radicals” J. Org. Chem. 2002, 67, 6195.
• Garner, P.; Anderson, J. T.; Dey, S. “S-(1-Oxido-2-pyridinyl)-1,1,3,3-tetramethylthiouronium Hexafluorophosphate (HOTT)” Electronic Encyclopedia of Reagents for Organic Synthesis.
• Garner, P.; Sherry, B.; Moilanen, S.; Huang, Y. “In Vitro Stability of α-Helical Peptide Nucleic Acids (αPNAs)” Bioorg. Med. Chem. Lett. 2001, 11, 2315.
• Garner, P.; Dogan, Ö.; Youngs, W. J.; Kennedy, V. O.; Protasiewicz, J.; Zaniewski, R. “Stereocontrolled 1,3-Dipolar Cycloadditions using Oppolzer's Camphor Sultam as the Chiral Auxiliary for Carboxyl Stabilized Azomethine Ylides” Tetrahedron, 2001, 57, 71.
• Garner, P.; Huang, Y.; Dey, S. “Enhancement of αPNA Binding Affinity and Specificity via Hydrophobic Interactions” ChemBioChem 2001, 2, 224.
• Dey, S.; Garner, P. “Synthesis of tert-Butoxycarbonyl (Boc) Protected Purines” J. Org. Chem. 2000, 65, 7697.
• Garner, P.; Anderson, J. T.; Turske, R. A. “Asymmetric Diels–Alder Chemistry Based on a New Chiral Auxiliary for 1-Hydroxyl Substituted Dienes” Chem. Commun. 2000, 1579.
• Garner, P.; Dey, S.; Huang, Y. “α-Helical Peptide Nucleic Acids (αPNAs): A New Paradigm for DNA-Binding Molecules” J. Am. Chem. Soc. 2000, 122, 2405.
• Dogan, Ö.; Garner, P. P. “Auxiliary Controlled Intramolecular 1,3-dipolar Cycloaddition Reactions of Chiral Azomethine Ylides” Tr. J. Chem. 2000, 24, 59.
• Garner, P.; Anderson, J. T. “Radical Based Asymmetric Synthesis: An Iterative Approach To 1,3,5...(2n+1) Polyols” Organic Letters 1999, 1, 1057.
• Garner, P.; Dey, S.; Huang, Y.; Zhang, X. “Modular Nucleic Acid Surrogates. Solid Phase Synthesis of Alpha-Helical Peptide Nucleic Acids (αPNAs)” Organic Letters 1999, 1, 403.
• Garner, P.; Anderson, J. T.; Dey, S.; Youngs, W. J.; Galat, K. “S-(1-Oxido-2-pyridinyl) 1,1,3,3-tetramethylthiouronium Hexafluorophosphate. A New Reagent for Preparing Hindered Barton Esters” J. Org. Chem. 1998, 63, 5732.
• Garner, P.; Yoo, J. U.; Sarabu, R.; Kennedy, V. O.; Youngs, W. J. “Stereocontrolled and Enantioselective Synthesis of the Branched 6-Amino-4,6-deoxyheptopyranuronic Acid Component of Amipurimycin” Tetrahedron 1998, 54, 9303.
• Garner, P.; Anderson, J. T. “A Rationally Designed Chiral Auxiliary for Hydroxyalkyl Radicals Leads to Exceptional ρ-Stereocontrol” Tetrahedron Lett. 1997, 38, 6647.
• Garner, P.; Cox, P. B.; Anderson, J. T.; Protasiewicz, J.; Zaniewski, R. “The Use of Silicon-Based Tethers to Control Diastereofacial Selectivity in Azomethine Ylide Cycloadditions” J. Org. Chem. 1997, 62, 493.