DEPARTMENT OF CHEMISTRY

Analytical Instrumentation Facility

Several nuclear magnetic resonance (NMR) spectrometers, including a Varian Inova 600 NMR, a Gemini 300 NMR and a Gemini 200 NMR spectrometer are located in the Analytical Instrumentaion Facility. These give access to all presently known multiple pulse measurements on both liquid and solid specimens. The NMR instrumentation makes it possible to perform a diversity of experiments on molecular structure and dynamics and reaction mechanisms. Nuclei routinely observable are 1H, 2H, 7Li,11B, 13C, 14N, 15N, 17O, 19F, 23Na, 27AI, 29Si, 31P, 33S, 77Se, 89Y, 107Ag, and 195Pt, with many others accessible.

A Kratos MS25RFA GC/Mass Spectrometer is also available, which has undergone recent upgrading of its data acquisition and handling systems. This dual-sector mass spectrometer has both CI (chemical ionization) and FAB (fast atom bombardment) capabilities in addition to the conventional EI (electron impact) source. A Varian Century Series E-112 electron paramagnetic resonance (EPR) spectrometer is also located in this facility.

Cleveland Center for Structural Biology (CCSB)

The Cleveland Center for Structural Biology (CCSB) is a joint venture between CWRU and the nearby Cleveland Clinic. It operates NMR instrumentation across campus including the systems located within the Analytical Instrumentation Facility. A Varian UnityPlus-600 MHz NMR spectrometer acquired in collaboration with the Medical School is located across the street from the Pytte Science Center. This NMR is equipped with numerous state of the art accessories including three broadbanded RF channels (all equipped with waveform generators for shaped pulses and GARP decoupling), a pulsed field gradient accessory for suppression of solvent resonances, and related software.

X-Ray Diffraction Facility

This facility, operated by Professor Protasiewicz is equipped with a state-of-the-art Bruker SMART APEX II CCD X-ray diffractometer and low temperature device for structural determination by X-ray crystallography. Peripheral equipment for structure solution and graphics presentation includes video-equipped microscopes and all software and computers for complete structural analyses.