case western reserve university


Department of Biology



Goodnough LH, Chang AT, Treloar C, Yang J, Scacheri PC, Atit RP.(2012). Twist1 mediates repression of chondrogenesis by β-catenin to promote cranial bone progenitor specification. Development, 139, p. 4428-38.

Myung PS, Takeo M, Ito M, Atit RP.(2012). Epithelial Wnt ligand secretion is required for adult hair follicle growth and regeneration.Journal of Investigative Dermatology, 133, p31-41.

Emily Hamburg and Radhika Atit (2012). Sustained beta-catenin activity in dermal fibroblasts is sufficient for skin fibrosis, Journal of Investigative Dermatology, 132, p2469-72.

Demeng Chen, Andrew Jarrell, Canting Guo, Richard Lang, Radhika Atit (2012). Dermal beta-catenin in response to ectodermal Wnt ligands are required for fibroblast proliferation and hair follicle initiation, Development, 139: 1522-33.

Jun Wei, F. Fang, Ann P. Lam, J.L. Sargent, Emily Hamburg, M.E. Hinchcliff, C. Gottardi, Radhika Atit, M.L. Whitfield, J. Varga (2012). Wnt/beta-catenin signaling is hyperactived in systemic sclerosis and induces smad-dependent fibrotic responses in mesenchymal cells,Arthritis and Rheumatism, 64, p2734-45.

Thu Tran, Andrew Jarrell, Gabriel Zentner, Isaac Brownell, Peter Scacheri, Radhika Atit (2010). Role of canonical Wnt signaling/beta-catenin in cranial dermal development, Development, 137: 3973-84.

Preethi Mani, Andrew Jarrell, John Myers, Radhika Atit (2010). Visualizing canonical Wnt signaling during mouse craniofacial development. Developmental Dynamics, 239:354-63.

Knothe Tate, ML; Falls, TD; McBride, SH; Atit, R., Knothe, UR (2008). Mechanical modulation of osteochondroprogenitor cell fate. Int. J. Biochem Cell Biol. 40 (12): 27020-38. (Review).

Jennifer Ohtola, John Myers, Batool Akhtar-Zaidi, Diana Zuzindlak, Pooja Sandesara, Karen Yeh, Susan Mackem, and Radhika Atit (2008). Beta-Catenin has sequential roles in the survival and specification of ventral dermis. Development 135:2321-2329.

Liu F, Chu EY, Watt B, Zhang Y, Gallant NM, Andl T, Yang SH, Lu MM, Piccolo S, Schmidt-Ullrich R, Taketo MM, Morrisey EE, Atit R, Dlugosz AA, Millar SE. (2008). Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Developmental Biology  313 p210-24

Atit R., Sgaier, S. Mohammed, O., Taketo, M., Dufort, D., Joyner, A., Niswander, L., Conlon, R. (2006). Beta-catenin activity is necessary and sufficient for dorsal dermal fate specification. in mouse. Developmental Biology, 296, p164-176.  

Atit, R. , Conlon, R, and Niswander, L. (2003).  EGFR signaling patterns the feather array by promoting interbud fate. Developmental Cell  4  p231-40

Rizvi, T.A, Ling, B., Huang, Y., Sidani, A., Atit, R., Largaespada, D.A., Boissy, R.E., and Ratner, N. (2002). A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve. J. Neuroscience  22 p.9831-40

Sherman, LS., Atit, R., Rosenbaum, T., Cox, A.D., Ratner, N. (2000). Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts. J Biol Chem., 275 p.30740-5.

Atit, R., Mitchell, K., Nguyen, L., Warshawksy, D., Ratner, N. (2000). The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57Bl/6 mice. Accepted at J. Invest. Dermatology, 114 p.1093-1100.

Atit, R., Crowe, M., Wenstrup, R., Greenhalgh, D., and Ratner, N. (1999). The Nf1, tumor suppressor gene is required for normal skin wound healing, fibroblast proliferation, and collagen deposition. J. Invest. Dermatology, 112 p.835-842.